Hippeastrine
Modify Date: 2024-01-20 16:25:16
Hippeastrine structure
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Common Name | Hippeastrine | ||
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| CAS Number | 477-17-8 | Molecular Weight | 315.32100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H17NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HippeastrineHippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect against topoisomerase I (Top I) with an IC50 at 7.25 μg/mL. Antiproliferative and anticancer activities[1]. |
| Name | hippeastrine |
|---|---|
| Synonym | More Synonyms |
| Description | Hippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect against topoisomerase I (Top I) with an IC50 at 7.25 μg/mL. Antiproliferative and anticancer activities[1]. |
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| Related Catalog | |
| In Vitro | Hippeastrine strongly inhibits the proliferation of HT-29 and Hep G2 cells in an intuitive dose-dependent manner with the IC50s at 3.98 μg/mL and 11.85 μg/mL, respectively, and also induces significant cellular morphological changes, which further validate our screening method and the potent antineoplastic effects[1]. |
| References |
| Molecular Formula | C17H17NO5 |
|---|---|
| Molecular Weight | 315.32100 |
| Exact Mass | 315.11100 |
| PSA | 68.23000 |
| LogP | 0.98080 |
| Hippeastrine |