CORM-3

Modify Date: 2025-08-21 18:35:03

CORM-3 structure	Common Name	CORM-3
	CAS Number	475473-26-8	Molecular Weight	296.62800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅H₄ClNO₅Ru	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of CORM-3

CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].

Name	Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)
Synonym	More Synonyms

Description	CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Foresti R, et al. Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol. 2004 Jun;142(3):453-60. [2]. Lee DW, et al. Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages. Biochem Biophys Res Commun. 2017 Nov 18;493(2):957-963. [3]. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.

Description

Related Catalog

Research Areas >> Inflammation/Immunology

References

[1]. Foresti R, et al. Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol. 2004 Jun;142(3):453-60.

[2]. Lee DW, et al. Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages. Biochem Biophys Res Commun. 2017 Nov 18;493(2):957-963.

[3]. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.

Molecular Formula	C₅H₄ClNO₅Ru
Molecular Weight	296.62800
Exact Mass	296.89800
PSA	112.85000
Storage condition	-20℃

Hazard Codes	N
RIDADR	NONH for all modes of transport

MFCD07364048

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CORM-3

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.