3'-Hydroxypterostilbene

Modify Date: 2025-09-18 19:04:14

3'-Hydroxypterostilbene Structure
3'-Hydroxypterostilbene structure
Common Name 3'-Hydroxypterostilbene
CAS Number 475231-21-1 Molecular Weight 272.296
Density 1.3±0.1 g/cm3 Boiling Point 469.7±45.0 °C at 760 mmHg
Molecular Formula C16H16O4 Melting Point N/A
MSDS N/A Flash Point 237.8±28.7 °C

 Use of 3'-Hydroxypterostilbene


3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

 Names

Name 3'-Hydroxypterostilbene
Synonym More Synonyms

 3'-Hydroxypterostilbene Biological Activity

Description 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].
Related Catalog
Target

Apoptosis[1] Autophagy[1]

References

[1]. Cheng TC, et al. Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors. PLoS One. 2014 Nov 12;9(11):e111814.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 469.7±45.0 °C at 760 mmHg
Molecular Formula C16H16O4
Molecular Weight 272.296
Flash Point 237.8±28.7 °C
Exact Mass 272.104858
PSA 58.92000
LogP 3.68
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.665
Storage condition -20℃

 Synonyms

1,2-Benzenediol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-
4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]-1,2-benzenediol
4-[2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol
4-(2-(3,5-dimethoxyphenyl)ethenyl)-1,2-benzenediol
4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol
4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
(E)-4-(3,5-Dimethoxystyryl)benzene-1,2-diol
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