beta-Eudesmol

Modify Date: 2024-01-05 16:41:51

beta-Eudesmol structure	Common Name	beta-Eudesmol
	CAS Number	473-15-4	Molecular Weight	222.366
	Density	1.0±0.1 g/cm3	Boiling Point	301.7±11.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₆O	Melting Point	72-74ºC
	MSDS	Chinese USA	Flash Point	108.6±15.6 °C

Use of beta-Eudesmol

Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1[1].

Name	β-eudesmol
Synonym	More Synonyms

Description	Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Metabolic Disease
References	[1]. Ohara K, et al. β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system. Sci Rep. 2017 Nov 17;7(1):15785. [2]. Ohara K, et al. Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oil. J Biol Chem. 2015 Jan 30;290(5):3161-71.

Description

Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1[1].

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Metabolic Disease

References

[1]. Ohara K, et al. β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system. Sci Rep. 2017 Nov 17;7(1):15785.

[2]. Ohara K, et al. Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oil. J Biol Chem. 2015 Jan 30;290(5):3161-71.

Density	1.0±0.1 g/cm3
Boiling Point	301.7±11.0 °C at 760 mmHg
Melting Point	72-74ºC
Molecular Formula	C₁₅H₂₆O
Molecular Weight	222.366
Flash Point	108.6±15.6 °C
Exact Mass	222.198364
PSA	20.23000
LogP	4.68
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.499
Storage condition	2-8°C

beta-Eudesmol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ9698500

CHEMICAL NAME :: 2-Naphthalenemethanol, decahydro-8-methylene-alpha,alpha,4a-trimethyl-, (2R-(2-alpha,4a- alpha,8a-beta)-

CAS REGISTRY NUMBER :: 473-15-4

LAST UPDATED :: 199703

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H26-O

MOLECULAR WEIGHT :: 222.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-13629

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	QJ9698500

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Acta. Pharm. 57(4) , 499-504, (2007)

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Nat. Prod. Commun. 5(7) , 1143-6, (2010)

The hydrodistillated leaf essential oil of Machilus pseudolongifolia was analyzed to determine its composition and yield. Seventy compounds were identified, the main components being beta-eudesmol (26...

2-[(2R,4aR,8aS)-4a-Methyl-8-methylenedecahydronaphthalen-2-yl]propan-2-ol

2-[(2R,4aR,8aS)-4a-methyl-8-methylidenedecahydronaphthalen-2-yl]propan-2-ol

Eudesm-4(14)-en-11-ol

2-[(2R,4aR,8aS)-4a-methyl-8-methylidene-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl]propan-2-ol

b-Eudesmol

2-[(2R,4aR,8aS)-4a-Methyl-8-methylenedecahydro-2-naphthalenyl]-2-propanol

Eudesmol. B.

2-Naphthalenemethanol, decahydro-α,α,4a-trimethyl-8-methylene-, (2R,4aR,8aS)-

beta-eudesmol

(+)-b-Eudesmol

rel-2-[(2R,4aR,8aS)-4a-methyl-8-methylenedecahydronaphthalen-2-yl]propan-2-ol

|A-Eudesmol

Eudesm-4(14)-en-11-ol (8CI)

1,2a,3,4,4a,5,6,7,8,8aa-Decahydro-a,a,4ab-trimethyl-8-methylene-2-naphthalenemethanol

b-Selinenol

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: beta-eudesmol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: beta-Eudesmol
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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