Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester

Modify Date: 2024-01-16 18:00:14

Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester Structure
Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester structure
Common Name Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester
CAS Number 4663-83-6 Molecular Weight 195.21500
Density 1.182 g/cm3 Boiling Point 375.8ºC at 760mmHg
Molecular Formula C10H13NO3 Melting Point N/A
MSDS N/A Flash Point 181.1ºC

 Use of Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester


Buramate exhibits neuroprotective and anticonvulsant activities.

 Names

Name 2-hydroxyethyl N-benzylcarbamate
Synonym More Synonyms

  Biological Activity

Description Buramate exhibits neuroprotective and anticonvulsant activities.
Related Catalog

 Chemical & Physical Properties

Density 1.182 g/cm3
Boiling Point 375.8ºC at 760mmHg
Molecular Formula C10H13NO3
Molecular Weight 195.21500
Flash Point 181.1ºC
Exact Mass 195.09000
PSA 58.56000
LogP 1.29600
Index of Refraction 1.542

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EY8747000
CHEMICAL NAME :
Carbamic acid, benzyl-, 2-hydroxyethyl ester
CAS REGISTRY NUMBER :
4663-83-6
BEILSTEIN REFERENCE NO. :
2838813
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H13-N-O3
MOLECULAR WEIGHT :
195.24
WISWESSER LINE NOTATION :
Q2OVM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 127,220,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 9,390,1951

 Safety Information

HS Code 2924299090

 Synthetic Route

~%

Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester Structure

Carbamic acid,N...

CAS#:4663-83-6

Literature: Delaby et al. Bulletin de la Societe Chimique de France, 1956 , p. 831,835 Full Text Show Details Viard; Piganiol Chim.et Ind.Sonderband 23.Congr.int.Chim.ind.Mailand, 1950 , p. 233,236 Full Text Show Details Hazard et al. Annales Pharmaceutiques Francaises, 1951 , vol. 9, p. 390,396

~46%

Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester Structure

Carbamic acid,N...

CAS#:4663-83-6

Detail
Literature: Shivarkar, Anandkumar B.; Gupte, Sunil P.; Chaudhari, Raghunath V. Synlett, 2006 , # 9 p. 1374 - 1378

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

AC-601
Buramate
Hyamate
Buramat
2-Benzylcarbamoyloxy-aethanol
2-Hydroxyethyl benzylcarbamate
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  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
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