4-Chlorobutyryl chloride

Modify Date: 2024-01-02 20:58:00

4-Chlorobutyryl chloride Structure
4-Chlorobutyryl chloride structure
Common Name 4-Chlorobutyryl chloride
CAS Number 4635-59-0 Molecular Weight 140.996
Density 1.2±0.1 g/cm3 Boiling Point 174.3±13.0 °C at 760 mmHg
Molecular Formula C4H6Cl2O Melting Point -47 °C
MSDS Chinese USA Flash Point 70.2±20.2 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name 4-Chlorobutyryl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 174.3±13.0 °C at 760 mmHg
Melting Point -47 °C
Molecular Formula C4H6Cl2O
Molecular Weight 140.996
Flash Point 70.2±20.2 °C
Exact Mass 139.979568
PSA 17.07000
LogP 1.44
Vapour Pressure 1.2±0.3 mmHg at 25°C
Index of Refraction 1.442

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EM1406000
CHEMICAL NAME :
Butanoyl chloride, 4-chloro-
CAS REGISTRY NUMBER :
4635-59-0
LAST UPDATED :
199710
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H6-Cl2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
650 mg/m3/4H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570772

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H302-H314-H330
Precautionary Statements P260-P280-P284-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive
Risk Phrases R22;R23;R35
Safety Phrases S26-S28-S36/37/39-S45-S28A
RIDADR UN 3390 6.1/PG 1
WGK Germany 1
RTECS EM1406000
Packaging Group II
Hazard Class 6.1
HS Code 29159080

 Synthetic Route

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles3

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N-Chloroacyl-6-O-triphenylmethylchitosans: useful intermediates for synthetic modifications of chitosan.

Biomacromolecules 6(2) , 858-63, (2005)

An efficient synthetic route was developed for the mild chloroacylation of chitosan with different chloroacyl chlorides. Full N-chloroacylation was obtained with this procedure without any O-acylation...

Radiosynthesis of (11)C-Levetiracetam: A Potential Marker for PET Imaging of SV2A Expression.

ACS Med. Chem. Lett. 5(10) , 1152-5, (2014)

The multistep preparation of (11)C-levetiracetam ((11)C-LEV) was carried out by a one-pot radiosynthesis with 8.3 ± 1.6% (n = 8) radiochemical yield in 50 ± 5.0 min. Briefly, the propionaldehyde was c...

Multikilogram-scale synthesis of a biphenyl carboxylic acid derivative using a Pd/C-mediated suzuki coupling approach. Ennis DS, et al.

Org. Process Res. Dev. 3(4) , 248-52, (1999)

 Synonyms

4-Chlorobutanoyl chloride
Butanoyl chloride, 4-chloro-
γ-Chlorobutyryl chloride
MFCD00000754
4-Chlorobutyryl chloride
4-Chlorobutyrylchloride
EINECS 225-059-1
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