(2-Chloroethyl)dimethylamine hydrochloride

Modify Date: 2024-01-02 15:02:52

(2-Chloroethyl)dimethylamine hydrochloride structure	Common Name	(2-Chloroethyl)dimethylamine hydrochloride
	CAS Number	4584-46-7	Molecular Weight	144.043
	Density	N/A	Boiling Point	57.8ºC at 760 mmHg
	Molecular Formula	C₄H₁₁Cl₂N	Melting Point	201-204 °C(lit.)
	MSDS	Chinese USA	Flash Point	21.6ºC
	Symbol	GHS06	Signal Word	Danger

Name	2-Dimethylaminoethyl chloride hydrochloride
Synonym	More Synonyms

Boiling Point	57.8ºC at 760 mmHg
Melting Point	201-204 °C(lit.)
Molecular Formula	C₄H₁₁Cl₂N
Molecular Weight	144.043
Flash Point	21.6ºC
Exact Mass	143.026855
PSA	3.24000
LogP	1.58880
Water Solubility	2000 g/L (20 ºC)

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KQ9020000

CHEMICAL NAME :: Ethylamine, 2-chloro-N,N-dimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 4584-46-7

LAST UPDATED :: 199804

DATA ITEMS CITED :: 17

MOLECULAR FORMULA :: C4-H10-Cl-N.Cl-H

MOLECULAR WEIGHT :: 144.06

WISWESSER LINE NOTATION :: G2N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 238 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Gastrointestinal - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Blood - hemorrhage Skin and Appendages - dermatitis, other (after systemic exposure)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 117 mg/kg/7D-I

TOXIC EFFECTS :: Behavioral - food intake (animal) Liver - hepatitis (hepatocellular necrosis), diffuse Nutritional and Gross Metabolic - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 720 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - rat Cells - not otherwise specified

DOSE/DURATION :: 100 umol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1697,1987

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H311-H315-H319-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P312
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases	R22;R24;R26;R36/37/38;R51/53;R68
Safety Phrases	S26-S36/37-S45-S61-S36/37/39-S28A
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	KQ9020000
Packaging Group	III
Hazard Class	6.1
HS Code	29211980

2-(Dimethylamin...

CAS#:108-01-0

~94%

(2-Chloroethyl)...

CAS#:4584-46-7

Literature: Fornasier, Roberto; Scrimin, Paolo; Tecilla, Paolo; Tonellato, Umberto Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 224 - 229

Dimethylamine

CAS#:124-40-3

2-Chloroethanol

CAS#:107-07-3

~59%

(2-Chloroethyl)...

CAS#:4584-46-7

Literature: CHINA PHARMACEUTICAL UNIVERSITY; Xiang, Hua; Wang, Tianlin; Xiao, Hong; You, Qidong; Yao, Yao; Li, Xiaobo; Liao, Qingjiang Patent: US2013/85140 A1, 2013 ; Location in patent: Paragraph 0056; 0057 ;

Precursor 3
CAS#:108-01-0 2-(Dimethylamin... CAS#:124-40-3 Dimethylamine CAS#:107-07-3 2-Chloroethanol
DownStream 10
CAS#:106823-66-9 N,N-dimethyl-2-... CAS#:1072-11-3 Ethanamine,2,2'... CAS#:42399-41-7 Diltiazem CAS#:14087-57-1 1,1-dichloro-N-...
CAS#:486-16-8 carbinoxamine CAS#:51344-13-9 N,N-dimethyl-2-... CAS#:221915-84-0 2-(3-Bromopheno... CAS#:18833-74-4 dimethyl-[2-(7,...
CAS#:18167-29-8 METHYL 2-[2-(DI... CAS#:22291-83-4 3-[2-(dimethyla...

HS Code	2921199090
Summary	2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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EINECS 224-970-1

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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (2-Chloroethyl)dimethylamine hydrochloride
Price: ￥118.0/100g ￥378.0/500g
Purity: 99.0%
Stocking Period: 2 Day
Contact: Liu jia

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Dimethylaminoethyl chloride hydrochloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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(2-Chloroethyl)dimethylamine hydrochloride

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MSDS

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HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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