(2-Chloroethyl)dimethylamine hydrochloride

Modify Date: 2025-08-21 11:33:27

(2-Chloroethyl)dimethylamine hydrochloride structure	Common Name	(2-Chloroethyl)dimethylamine hydrochloride
	CAS Number	4584-46-7	Molecular Weight	144.043
	Density	N/A	Boiling Point	57.8ºC at 760 mmHg
	Molecular Formula	C₄H₁₁Cl₂N	Melting Point	201-204 °C(lit.)
	MSDS	Chinese USA	Flash Point	21.6ºC
	Symbol	GHS06	Signal Word	Danger

Name	2-Dimethylaminoethyl chloride hydrochloride
Synonym	More Synonyms

Boiling Point	57.8ºC at 760 mmHg
Melting Point	201-204 °C(lit.)
Molecular Formula	C₄H₁₁Cl₂N
Molecular Weight	144.043
Flash Point	21.6ºC
Exact Mass	143.026855
PSA	3.24000
LogP	1.58880
InChIKey	LQLJZSJKRYTKTP-UHFFFAOYSA-N
SMILES	CN(C)CCCl.Cl
Water Solubility	2000 g/L (20 ºC)

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KQ9020000

CHEMICAL NAME :: Ethylamine, 2-chloro-N,N-dimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 4584-46-7

LAST UPDATED :: 199804

DATA ITEMS CITED :: 17

MOLECULAR FORMULA :: C4-H10-Cl-N.Cl-H

MOLECULAR WEIGHT :: 144.06

WISWESSER LINE NOTATION :: G2N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 238 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Gastrointestinal - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Blood - hemorrhage Skin and Appendages - dermatitis, other (after systemic exposure)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 117 mg/kg/7D-I

TOXIC EFFECTS :: Behavioral - food intake (animal) Liver - hepatitis (hepatocellular necrosis), diffuse Nutritional and Gross Metabolic - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 720 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - rat Cells - not otherwise specified

DOSE/DURATION :: 100 umol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1697,1987

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H311-H315-H319-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P312
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases	R22;R24;R26;R36/37/38;R51/53;R68
Safety Phrases	S26-S36/37-S45-S61-S36/37/39-S28A
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	KQ9020000
Packaging Group	III
Hazard Class	6.1
HS Code	29211980

2-(Dimethylamin...

CAS#:108-01-0

~94%

(2-Chloroethyl)...

CAS#:4584-46-7

Literature: Fornasier, Roberto; Scrimin, Paolo; Tecilla, Paolo; Tonellato, Umberto Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 224 - 229

Dimethylamine

CAS#:124-40-3

2-Chloroethanol

CAS#:107-07-3

~59%

(2-Chloroethyl)...

CAS#:4584-46-7

Literature: CHINA PHARMACEUTICAL UNIVERSITY; Xiang, Hua; Wang, Tianlin; Xiao, Hong; You, Qidong; Yao, Yao; Li, Xiaobo; Liao, Qingjiang Patent: US2013/85140 A1, 2013 ; Location in patent: Paragraph 0056; 0057 ;

Precursor 3
CAS#:108-01-0 2-(Dimethylamin... CAS#:124-40-3 Dimethylamine CAS#:107-07-3 2-Chloroethanol
DownStream 10
CAS#:106823-66-9 N,N-dimethyl-2-... CAS#:1072-11-3 Ethanamine,2,2'... CAS#:42399-41-7 Diltiazem CAS#:14087-57-1 1,1-dichloro-N-...
CAS#:486-16-8 carbinoxamine CAS#:51344-13-9 N,N-dimethyl-2-... CAS#:221915-84-0 2-(3-Bromopheno... CAS#:18833-74-4 dimethyl-[2-(7,...
CAS#:18167-29-8 METHYL 2-[2-(DI... CAS#:22291-83-4 3-[2-(dimethyla...

HS Code	2921199090
Summary	2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

N-(2-chloroethyl)-N,N-dimethylamine hydrochloride

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MFCD00012516

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DMC

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N,N-DimethylaminoChloroethaneHCl

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2-chloro-N,N-dimethylaminoethane hydrochloride

2-Dimethylaminoethyl

N,N-dimethylamino-2-chloroethane hydrochloride

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EINECS 224-970-1

1-chloro-2-(N,N-dimethylamino)ethane hydrochloride

N,N-DIMETHYL(2-CHLOROETHYL)-AMINE

2-Chloro-N,N-dimethylethanamine hydrochloride

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (2-Chloroethyl)dimethylamine hydrochloride
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (2-Chloroethyl)dimethylamine hydrochloride
Price: ￥118.0/100g ￥378.0/500g
Purity: 99.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Dimethylaminoethyl chloride hydrochloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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(2-Chloroethyl)dimethylamine hydrochloride

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.