4-fluorobenzhydrazide

Modify Date: 2024-01-02 20:25:14

4-fluorobenzhydrazide Structure
4-fluorobenzhydrazide structure
Common Name 4-fluorobenzhydrazide
CAS Number 456-06-4 Molecular Weight 154.142
Density 1.3±0.1 g/cm3 Boiling Point 299.8ºC at 760 mmHg
Molecular Formula C7H7FN2O Melting Point 162-166 °C(lit.)
MSDS Chinese USA Flash Point 135.1ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Fluorobenzhydrazide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 299.8ºC at 760 mmHg
Melting Point 162-166 °C(lit.)
Molecular Formula C7H7FN2O
Molecular Weight 154.142
Flash Point 135.1ºC
Exact Mass 154.054245
PSA 55.12000
LogP 0.47
Vapour Pressure 0.392mmHg at 25°C
Index of Refraction 1.553

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH1310000
CHEMICAL NAME :
Benzoic acid, p-fluoro-, hydrazide
CAS REGISTRY NUMBER :
456-06-4
BEILSTEIN REFERENCE NO. :
1946324
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H7-F-N2-O
MOLECULAR WEIGHT :
154.16
WISWESSER LINE NOTATION :
ZMVR DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01168

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DH1310000
HS Code 2928000090

 Synthetic Route

~99%

4-fluorobenzhydrazide Structure

4-fluorobenzhyd...

CAS#:456-06-4

Literature: ENDO PHARMACEUTICALS INC.; SMITH, Roger, Astbury; KETHIRI, Raghava, Reddy; KRISTAM, Rajendra; LAPING, Nicholas, James; VENKATESHAPPA, Chandregowda; KULKARNI, Bheemashankar; DEVRAJ, Rajesh; DEWANG, Purushottam Patent: WO2013/49559 A1, 2013 ; Location in patent: Page/Page column 92 ;

~87%

4-fluorobenzhydrazide Structure

4-fluorobenzhyd...

CAS#:456-06-4

Literature: Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav; Rao, Janapala Venkateswara; Pamanji; Velatooru Letters in Drug Design and Discovery, 2012 , vol. 9, # 3 p. 276 - 281

~83%

4-fluorobenzhydrazide Structure

4-fluorobenzhyd...

CAS#:456-06-4

Literature: Peng, Yanqing; Song, Gonghua Journal of Chemical Research - Part S, 2003 , # 12 p. 768 - 769

~66%

4-fluorobenzhydrazide Structure

4-fluorobenzhyd...

CAS#:456-06-4

Literature: Gulerman; Rollas Farmaco, 1997 , vol. 52, # 11 p. 691 - 695

~%

4-fluorobenzhydrazide Structure

4-fluorobenzhyd...

CAS#:456-06-4

Literature: Gulerman; Rollas Farmaco, 1997 , vol. 52, # 11 p. 691 - 695

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

4-Fluoro-benzoic acid hydrazide
Benzoic acid, 4-fluoro-, hydrazide
4-Fluorobenzoylhydrazine
4-Fluorobenzohydrazide Hydrate
4-Fluorobenzoichydrazide
4-Fluorobenzoic Hydrazide
4-fluorobenzhydrazide
4-Fluorobenzohydrazide
MFCD00060562