2-Bromo-5-(piperazin-1-yl)pyrazine

Modify Date: 2024-01-11 08:52:02

2-Bromo-5-(piperazin-1-yl)pyrazine Structure
2-Bromo-5-(piperazin-1-yl)pyrazine structure
Common Name 2-Bromo-5-(piperazin-1-yl)pyrazine
CAS Number 446286-90-4 Molecular Weight 243.104
Density 1.5±0.1 g/cm3 Boiling Point 380.6±42.0 °C at 760 mmHg
Molecular Formula C8H11BrN4 Melting Point N/A
MSDS N/A Flash Point 184.0±27.9 °C

 Names

Name 2-bromo-5-piperazin-1-ylpyrazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 380.6±42.0 °C at 760 mmHg
Molecular Formula C8H11BrN4
Molecular Weight 243.104
Flash Point 184.0±27.9 °C
Exact Mass 242.016708
PSA 41.05000
LogP 0.82
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.584
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

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2-Bromo-5-(piperazin-1-yl)pyrazine Structure

2-Bromo-5-(pipe...

CAS#:446286-90-4

Literature: Barta, Thomas E.; Becker, Daniel P.; Bedell, Louis J.; Boehm, Terri L.; Brown, David L.; Carroll, Jeffery N.; Chen, Yiyuan; Fobian, Yvette M.; Freskos, John N.; Gasiecki, Alan F.; Grapperhaus, Margaret L.; Heintz, Robert M.; Hockerman, Susan L.; Kassab, Darren J.; Khanna, Ish K.; Kolodziej, Stephen A.; Massa, Mark A.; McDonald, Joseph J.; Mischke, Brent V.; Mischke, Deborah A.; Mullins, Patrick B.; Nagy, Mark A.; Norton, Monica B.; Rico, Joseph G.; Schmidt, Michelle A.; Stehle, Nathan W.; Talley, John J.; Vernier, William F.; Villamil, Clara I.; Wang, Lijuan J.; Wynn, Thomas A. Patent: US2005/9838 A1, 2005 ; Location in patent: Page 296 ; US 20050009838 A1

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2-Bromo-5-(piperazin-1-yl)pyrazine Structure

2-Bromo-5-(pipe...

CAS#:446286-90-4

Literature: NEUROGEN CORPORATION Patent: WO2007/16496 A2, 2007 ; Location in patent: Page/Page column 54 ; WO 2007/016496 A2

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2-Bromo-5-(piperazin-1-yl)pyrazine Structure

2-Bromo-5-(pipe...

CAS#:446286-90-4

Literature: Wang, Tao; Zhang, Zhongxing; Meanwell, Nicholas A.; Kadow, John F.; Yin, Zhiwei; Xue, Qiufen May; Regueiro-Ren, Alicia; Matiskella, John D.; Ueda, Yasutsugu Patent: US2004/110785 A1, 2004 ; Location in patent: Page 117 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Pyrazine, 2-bromo-5-(1-piperazinyl)-
2-Bromo-5-(1-piperazinyl)pyrazine