K00546
Modify Date: 2025-08-27 18:11:43
K00546 structure
|
Common Name | K00546 | ||
|---|---|---|---|---|
| CAS Number | 443798-47-8 | Molecular Weight | 425.436 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 649.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C15H13F2N7O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 346.4±34.3 °C | |
Use of K00546K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively. |
| Name | K-00546 |
|---|---|
| Synonym | More Synonyms |
| Description | K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively. |
|---|---|
| References | References 1. Fedorov O, et al. Chem Biol. 2011 Jan 28;18(1):67-76. 2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17. View Related Products by Target Cdc2-like Kinase (CLK) |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 649.1±65.0 °C at 760 mmHg |
| Molecular Formula | C15H13F2N7O2S2 |
| Molecular Weight | 425.436 |
| Flash Point | 346.4±34.3 °C |
| Exact Mass | 425.054016 |
| LogP | 1.27 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.755 |
| MFCD09264159 |
| LFR1253W75 |
| CDK1/2 Inhibitor III |
| 1H-1,2,4-Triazole-1-carbothioamide, 5-amino-3-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)- |
| K-00546 |
| 5-Amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide |