CSV0C018875

Modify Date: 2024-01-09 17:35:38

CSV0C018875 structure	Common Name	CSV0C018875
	CAS Number	442150-41-6	Molecular Weight	312.79
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇ClN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CSV0C018875

CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor. CSV0C018875 exhibits lesser cytotoxicity than BIX-01294[1].

Name	CSV0C018875

Description	CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor. CSV0C018875 exhibits lesser cytotoxicity than BIX-01294[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	G9a
In Vitro	CSV0C018875 (2.5-20 μM; 48 hours) inhibits the levels of H3K9me2 modifications in the histones[1]. Western Blot Analysis[1] Cell Line: HEK293 cells Concentration: 2.5 μM, 10 μM, 20 μM Incubation Time: 48 hours Result: Inhibited the enzymatic activity of G9a in a dose-dependent manner in HEK293 cells.
References	[1]. M Ramya Chandar Charles, et al. Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening. Biochimie. 2020 Jan;168:220-230.

Molecular Formula	C₁₈H₁₇ClN₂O
Molecular Weight	312.79

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 6-chloro-N-(4-ethoxyphenyl)-2-methylquinolin-4-amine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: CSV0C018875
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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