TIE-2/VEGFR-2 kinase-IN-3

Modify Date: 2025-10-16 07:21:56

TIE-2/VEGFR-2 kinase-IN-3 structure	Common Name	TIE-2/VEGFR-2 kinase-IN-3
	CAS Number	433224-09-0	Molecular Weight	519.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₇F₄N₅O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TIE-2/VEGFR-2 kinase-IN-3

TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 6.9 nM and 3.5 nM, respectively. TIE-2/VEGFR-2 kinase-IN-3 can be used for the research of angiogenesis[1].

Name	TIE-2/VEGFR-2 kinase-IN-3

Description	TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 6.9 nM and 3.5 nM, respectively. TIE-2/VEGFR-2 kinase-IN-3 can be used for the research of angiogenesis[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	Tie2:6.9 nM (IC50) VEGFR-2:3.5 nM (IC50)
References	[1]. Hasegawa M, et al. Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors. J Med Chem. 2007 Sep 6;50(18):4453-70.

Molecular Formula	C₂₃H₁₇F₄N₅O₃S
Molecular Weight	519.47
InChIKey	KBJVFZCXZGSCFO-UHFFFAOYSA-N
SMILES	COC(=O)Nc1nc2ccc(Sc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1

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TIE-2/VEGFR-2 kinase-IN-3

Use of TIE-2/VEGFR-2 kinase-IN-3

Names

TIE-2/VEGFR-2 kinase-IN-3 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.