resveratrol triacetate

Modify Date: 2024-01-03 00:17:55

resveratrol triacetate Structure
resveratrol triacetate structure
Common Name resveratrol triacetate
CAS Number 42206-94-0 Molecular Weight 354.353
Density 1.2±0.1 g/cm3 Boiling Point 504.8±50.0 °C at 760 mmHg
Molecular Formula C20H18O6 Melting Point 117.0 to 121.0 °C
MSDS Chinese USA Flash Point 221.4±30.2 °C
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

 Use of resveratrol triacetate


Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects[1].

 Names

Name Triacetylresveratrol
Synonym More Synonyms

 resveratrol triacetate Biological Activity

Description Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects[1].
Related Catalog
Target

NF-κB

STAT3

In Vitro Triacetylresveratrol significantly down-regulates anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability, and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].
References

[1]. Duan J, et al.  In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFκB signaling in pancreatic cancer cells.Sci Rep. 2016 Aug 19;6:31672.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 504.8±50.0 °C at 760 mmHg
Melting Point 117.0 to 121.0 °C
Molecular Formula C20H18O6
Molecular Weight 354.353
Flash Point 221.4±30.2 °C
Exact Mass 354.110352
PSA 78.90000
LogP 2.94
Appearance of Characters white to tan
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.600
Storage condition room temp
Water Solubility DMSO: ≥18mg/mL

 Safety Information

Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger
Hazard Statements H315-H317-H318-H335-H400
Precautionary Statements P261-P273-P280-P305 + P351 + P338
Hazard Codes Xi,N
Risk Phrases 37/38-41-43-50/53
Safety Phrases 26-36/37/39-60-61
RIDADR UN 3077 9 / PGIII
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1,3-Benzenediol, 5-[(E)-2-[4-(acetyloxy)phenyl]ethenyl]-, diacetate
3-Acetoxy-5-[(E)-2-(4-acetoxyphenyl)vinyl]phenyl acetate
5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-Benzenediol-1,3-diacetate
Acetyl trans-resveratrol
(E)-5-(4-Acetoxystyryl)-1,3-phenylene diacetate
Triacetyl resveratrol
3,4',5-Triacetoxy-trans-stilbene
Acetyl-trans-resveratrol
Acetic acid 4-[2-(3,5-diacetoxyphenyl)vinyl]phenyl ester
resveratrol triacetate
Acetyl-resveratrol
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