grapiprant
Modify Date: 2024-01-04 17:42:36
grapiprant structure
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Common Name | grapiprant | ||
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| CAS Number | 415903-37-6 | Molecular Weight | 491.605 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C26H29N5O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of grapiprantGrapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2).Target: prostaglandin receptorin vitro: Grapiprant is a novel pharmacologically active ingredient, acts as a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). [1]in vivo: Grapiprant is currently under development for use in humans and dogs for the control of pain and inflammation associated with osteoarthritis. [1] Results suggested the safety of long-term oral administration of grapiprant to dogs. Efficacy of grapiprant in the treatment of dogs with osteoarthritis needs to be evaluated in other studies. [2] |
| Name | Grapiprant |
|---|---|
| Synonym | More Synonyms |
| Description | Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2).Target: prostaglandin receptorin vitro: Grapiprant is a novel pharmacologically active ingredient, acts as a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). [1]in vivo: Grapiprant is currently under development for use in humans and dogs for the control of pain and inflammation associated with osteoarthritis. [1] Results suggested the safety of long-term oral administration of grapiprant to dogs. Efficacy of grapiprant in the treatment of dogs with osteoarthritis needs to be evaluated in other studies. [2] |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C26H29N5O3S |
| Molecular Weight | 491.605 |
| Exact Mass | 491.199097 |
| LogP | 4.56 |
| Index of Refraction | 1.647 |
| Storage condition | 2-8℃ |
| N-{2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}-N'-[(4-methylphenyl)sulfonyl]urea |
| CJ-023,423 |
| MR10A7 |
| N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide |
| grapiprant |
| Benzenesulfonamide, N-[[[2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methyl- |
| RQ-00000007 |
| AAT-007 |
| UNII:J9F5ZPH7NB |
| 2-Ethyl-4,6-dimethyl-1-[4-[2-[[[[(4-methylphenyl)sulfonyl]amino]carbonyl]amino]ethyl]phenyl]-1H-imidazo[4,5-c]pyridine |