2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

Modify Date: 2025-08-25 13:11:28

2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine Structure
2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine structure
Common Name 2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine
CAS Number 40896-58-0 Molecular Weight 491.68
Density N/A Boiling Point N/A
Molecular Formula C16H16BrClN4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine


2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name m-Tolyl-p-acetylphenyldisulfid

  Biological Activity

Description 2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C16H16BrClN4O7
Molecular Weight 491.68
Exact Mass 247.04900
PSA 76.62000
LogP 4.95780
InChIKey FALQPDDXFMGVNW-SDBHATRESA-N
SMILES CC(=O)OCC1OC(n2cnc3c(Cl)nc(Br)nc32)C(OC(C)=O)C1OC(C)=O
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