dexamethasone oxetanone
Modify Date: 2025-08-27 19:00:59
dexamethasone oxetanone structure
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Common Name | dexamethasone oxetanone | ||
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| CAS Number | 4089-36-5 | Molecular Weight | 374.44600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H27FO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of dexamethasone oxetanoneDexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms[1][2]. |
| Name | (8S,10S,11S,13S,14S,16R)-9-fluoro-11-hydroxy-10,13,16-trimethylspiro[6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17,2'-oxetane]-3,3'-dione |
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| Synonym | More Synonyms |
| Description | Dexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms[1][2]. |
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| Related Catalog | |
| In Vitro | Dexamethasone oxetanone (1 μM) exhibits significant quantities of agonist activity with transfected PR in CV-1 cells[2]. |
| References |
| Molecular Formula | C22H27FO4 |
|---|---|
| Molecular Weight | 374.44600 |
| Exact Mass | 374.18900 |
| PSA | 63.60000 |
| LogP | 2.94130 |
| Dexamethasone oxetanone |