3-Methylpyridine-2-carboxylic acid

Modify Date: 2024-01-02 17:30:43

3-Methylpyridine-2-carboxylic acid Structure
3-Methylpyridine-2-carboxylic acid structure
Common Name 3-Methylpyridine-2-carboxylic acid
CAS Number 4021-07-2 Molecular Weight 137.136
Density 1.2±0.1 g/cm3 Boiling Point 300.6±22.0 °C at 760 mmHg
Molecular Formula C7H7NO2 Melting Point 114-118 °C
MSDS Chinese USA Flash Point 135.6±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3-Methylpyridine-2-carboxylic Acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 300.6±22.0 °C at 760 mmHg
Melting Point 114-118 °C
Molecular Formula C7H7NO2
Molecular Weight 137.136
Flash Point 135.6±22.3 °C
Exact Mass 137.047684
PSA 50.19000
LogP 0.36
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.561

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

~82%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Yaremenko, Anatoliy G.; Volochnyuk, Dmitriy M.; Shelyakin, Vyacheslav V.; Grygorenko, Oleksandr O. Tetrahedron, 2013 , vol. 69, # 33 p. 6799 - 6803

~75%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Meiji Seika Kaisha, Ltd. Patent: EP1180514 A1, 2002 ; Location in patent: Example 103 ;

~91%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Epsztajn, Jan; Bieniek, Adam; Plotka, Mieczyslaw W. Journal of Chemical Research, Miniprint, 1986 , # 1 p. 442 - 474

~0%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Dunn Organic Preparations and Procedures International, 1999 , vol. 31, # 1 p. 120 - 123

~%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 7 p. 1501 - 1505

~%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Journal of the American Chemical Society, , vol. 74, p. 5967,5969

~%

3-Methylpyridine-2-carboxylic acid Structure

3-Methylpyridin...

CAS#:4021-07-2

Literature: Journal of Medicinal Chemistry, , vol. 27, # 2 p. 216 - 223

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

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Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3-methyl-picolinic acid.

Biometals 23(1) , 99-118, (2010)

Crystal structure analysis of the zinc complex establishes it as a distorted octahedral complex, bis(3-methylpicolinato-kappa(2) N,O)(2)(1,10-phenanthroline-kappa(2) N,N)-zinc(II) pentahydrate, [Zn(3-...

Ozonolysis of some 8-alkoxyquinolines, and synthesis of a precursor to the non-sedating antihistamine Claritin. Eichler MC and Grayson DH.

ARKIVOC 6 , 38-53, (2014)

Synthesis and characterization of copper (II) complexes with 3-methylpicolinic acid. Crystal and molecular structure of bis (3-methylpicolinato-N,O)(4-picoline) copper (II). Kukovec BM, et al.

J. Coord. Chem. 61(19) , 3092-3101, (2008)

 Synonyms

2-Pyridinecarboxylic acid, 3-methyl-
3-Methylpicolinic acid
3-Methyl-2-pyridinecarboxylic acid
3-Methylpyridine-2-carboxylic acid
MFCD00191553