UK-396082
Modify Date: 2024-02-01 15:34:23
UK-396082 structure
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Common Name | UK-396082 | ||
|---|---|---|---|---|
| CAS Number | 400044-47-5 | Molecular Weight | 239.31400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H21N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UK-396082UK‑396082 is a potent thrombin activated fibrinolytic inhibitor (TAFI) inhibitor. UK‑396082 increases plasmin activity and induces a parallel decrease in ECM levels. UK‑396082 can be used in research of chronic kidney disease (CKD)[1]. |
| Name | (2S)-5-amino-2-[(1-propylimidazol-4-yl)methyl]pentanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | UK‑396082 is a potent thrombin activated fibrinolytic inhibitor (TAFI) inhibitor. UK‑396082 increases plasmin activity and induces a parallel decrease in ECM levels. UK‑396082 can be used in research of chronic kidney disease (CKD)[1]. |
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| Related Catalog | |
| In Vitro | UK‑396082 (0-1000 nM; NRK52E 细胞; 96 小时) 以剂量依赖性方式诱导 TAFI 活性[1]。 UK‑396082 (500 nM; 24 h) 增加 NRK52E 细胞 (+109%) 和 NRK49F 成纤维细胞 (+38.3%) 中的纤溶酶活性[1]。 UK‑396082 (500 nM; 24 h; NRK52E 细胞) 使 ECM 水平降低 46%[1]。 |
| References |
| Molecular Formula | C12H21N3O2 |
|---|---|
| Molecular Weight | 239.31400 |
| Exact Mass | 239.16300 |
| PSA | 81.14000 |
| LogP | 1.97560 |
| (2s)-5-Amino-2-[(1-Propyl-1h-Imidazol-4-Yl)methyl]pentanoic Acid |
| UK-396,082 |
| UNII-2Q5861SUIG |