Lodenafil carbonate

Modify Date: 2024-01-03 11:19:26

Lodenafil carbonate Structure
Lodenafil carbonate structure
Common Name Lodenafil carbonate
CAS Number 398507-55-6 Molecular Weight 1035.20000
Density N/A Boiling Point 1109.0±75.0 °C(Predicted)
Molecular Formula C47H62N12O11S2 Melting Point 229-231 °C
MSDS N/A Flash Point N/A

 Use of Lodenafil carbonate


Lodenafil carbonate, a dimer that acts as a prodrug delivering Lodenafil in vivo, is an orally active phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED)[1][2].

 Names

Name bis[2-[4-[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]sulfonylpiperazin-1-yl]ethyl] carbonate
Synonym More Synonyms

 Lodenafil carbonate Biological Activity

Description Lodenafil carbonate, a dimer that acts as a prodrug delivering Lodenafil in vivo, is an orally active phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED)[1][2].
Related Catalog
Target

PDE5

References

[1]. Glina S, et al. Efficacy and tolerability of lodenafil carbonate for oral therapy in erectile dysfunction: a phase II clinical trial. J Sex Med. 2009 Feb;6(2):553-7.

[2]. Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591(1-3):189-95.

 Chemical & Physical Properties

Boiling Point 1109.0±75.0 °C(Predicted)
Melting Point 229-231 °C
Molecular Formula C47H62N12O11S2
Molecular Weight 1035.20000
Exact Mass 1034.41000
PSA 279.13000
LogP 5.04220

 Synonyms

Lodenafil Carbonate
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