Cupressuflavone

Modify Date: 2024-01-07 06:53:54

Cupressuflavone Structure
Cupressuflavone structure
Common Name Cupressuflavone
CAS Number 3952-18-9 Molecular Weight 538.46
Density N/A Boiling Point 1083.4ºC at 760mmHg
Molecular Formula C30H18O10 Melting Point >400ºC
MSDS N/A Flash Point 609ºC

 Use of Cupressuflavone


Cupressuflavone is a natural product that can be found in Cupressus macrocarpa. Cupressuflavone exhibits anti-inflammatory and antiulcerogenic activities. Cupressuflavone also show protective effects against CCl4-induced hepato- and nephrotoxicity in mice[1][2][3].

 Names

Name cupressuflavone
Synonym More Synonyms

 Cupressuflavone Biological Activity

Description Cupressuflavone is a natural product that can be found in Cupressus macrocarpa. Cupressuflavone exhibits anti-inflammatory and antiulcerogenic activities. Cupressuflavone also show protective effects against CCl4-induced hepato- and nephrotoxicity in mice[1][2][3].
Related Catalog
In Vitro Cupressuflavone (40-160 mg/kg; p.o. once daily for 5 days) 在肝脏和肾脏组织中通过增强抗氧化防御状态、减少脂质过氧化和防止 CCl4 诱导的病理变化来对抗氧化应激[1]。 Cupressuflavone (40-160 mg/kg; p.o.) 在40, 100, 160 mg/kg 剂量下分别抑制角叉菜胶诱导的炎症爪水肿 55%、60% 和 64%[2]。
References

[1]. Al-Sayed E, et, al. Protective role of Cupressuflavone from Cupressus macrocarpa against carbon tetrachloride-induced hepato- and nephrotoxicity in mice. Planta Med. 2014 Dec;80(18):1665-71.  

[2]. Al-Sayed E, et, al. Anti-inflammatory and analgesic activities of cupressuflavone from Cupressus macrocarpa: Impact on pro-inflammatory mediators. Drug Dev Res. 2018 Feb;79(1):22-28.  

[3]. Koriem KMM, et, al. Protective effect of Cupressus sempervirens extract against indomethacin-induced gastric ulcer in rats. Interdiscip Toxicol. 2015 Mar;8(1):25-34.  

 Chemical & Physical Properties

Boiling Point 1083.4ºC at 760mmHg
Melting Point >400ºC
Molecular Formula C30H18O10
Molecular Weight 538.46
Flash Point 609ºC
Exact Mass 538.09000
PSA 181.80000
LogP 5.13400
Index of Refraction 1.793

 Synonyms

8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
8,8'-Biapigenin
Cupressuflavone
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