Adaptaquin
Modify Date: 2025-08-27 14:06:59
Adaptaquin structure
|
Common Name | Adaptaquin | ||
|---|---|---|---|---|
| CAS Number | 385786-48-1 | Molecular Weight | 377.824 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 650.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C21H16ClN3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 347.4±31.5 °C | |
Use of AdaptaquinAdaptaquin is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PHD2), with an IC50 of 2 μM. Adaptaquin can inhibit lipid peroxidation and maintain mitochondrial function[1][2]. |
| Name | Adaptaquin |
|---|---|
| Synonym | More Synonyms |
| Description | Adaptaquin is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PHD2), with an IC50 of 2 μM. Adaptaquin can inhibit lipid peroxidation and maintain mitochondrial function[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2 μM (HIF-PHD2)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 650.9±55.0 °C at 760 mmHg |
| Molecular Formula | C21H16ClN3O2 |
| Molecular Weight | 377.824 |
| Flash Point | 347.4±31.5 °C |
| Exact Mass | 377.093109 |
| LogP | 4.63 |
| Appearance of Characters | Tan solid |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.753 |
| Storage condition | Store at -20℃ |
| Water Solubility | Soluble to 100 mM in DMSO |
| MFCD02655485 |
| 8-Quinolinol, 7-[(4-chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]- |
| 7-{(4-Chlorophenyl)[(3-hydroxypyridin-2-yl)amino]methyl}quinolin-8-ol |
| 7-{(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl}-8-quinolinol |