Climbazole

Modify Date: 2024-01-02 19:33:29

Climbazole Structure
Climbazole structure
 Common Name Climbazole
CAS Number 38083-17-9 Molecular Weight 292.761
Density 1.2±0.1 g/cm3 Boiling Point 447.5±40.0 °C at 760 mmHg
Molecular Formula C15H17ClN2O2 Melting Point 96-100°C
MSDS Chinese USA Flash Point 224.4±27.3 °C
Symbol GHS07 GHS09
GHS07, GHS09		 Signal Word Warning

 Use of Climbazole


Climbazole is a topical antifungal agent, commonly used in the treatment of human fungal skin infections, such as dandruff and eczema.

 Names

Name Climbazole
Synonym More Synonyms

 Climbazole Biological Activity

Description Climbazole is a topical antifungal agent, commonly used in the treatment of human fungal skin infections, such as dandruff and eczema.
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 447.5±40.0 °C at 760 mmHg
Melting Point 96-100°C
Molecular Formula C15H17ClN2O2
Molecular Weight 292.761
Flash Point 224.4±27.3 °C
Exact Mass 292.097870
PSA 44.12000
LogP 3.25
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.561
Storage condition -20°C Freezer

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EL7085000
CHEMICAL NAME :
2-Butanone, 1-(p-chlorophenoxy)-3,3-dimethyl-1-(1-imidazolyl)-
CAS REGISTRY NUMBER :
38083-17-9
BEILSTEIN REFERENCE NO. :
0618020
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H17-Cl-N2-O2
MOLECULAR WEIGHT :
292.79
WISWESSER LINE NOTATION :
T5N CNJ AYOR DG&VX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,832,1986

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H410
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22
Safety Phrases 60-61
RIDADR UN 3077
RTECS EL7085000
HS Code 2933290012

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2933290012
Summary 2933290012 1-((2-chlorophenyl)diphenylmethyl)-1h-imidazole。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

 Articles9

More Articles
Enhanced efficacy and sensory properties of an anti-dandruff shampoo containing zinc pyrithione and climbazole.

Int. J. Cosmet. Sci. 35(1) , 78-83, (2013)

Dandruff is a common complaint and is suffered by as much as half of the population at some time post puberty. The condition is characterized by the presence of flakes on the scalp and in the hair, an...
Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff.

Int. J. Cosmet. Sci. 33(3) , 276-82, (2011)

Dandruff is a chronic scalp disorder characterized by scaling and itching. A successful anti-dandruff shampoo not only has to provide superior anti-dandruff relief to ensure patient compliance. It als...
[Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography].

Wei Sheng Yan Jiu 34(5) , 626-8, (2005)

A high performance liquid chromatography method was established for determination of antidangdruff agent salicylic acid,zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo on a C18 colu...

 Synonyms

2-Butanone, 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-
Crinipan AD
1-(4-chlorophenoxy)-3,3-dimethyl-1-(imidazol-1-yl)-butan-2-one
CLIMBAZOL
1-(4-chloro-phenoxy)-1-imidazol-1-yl-3,3-dimethyl-butan-2-one
1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethyl-2-butanone
(RS)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one
MFCD00055505
1-(4-Chlorphenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-on
baypival
rac-(1R)-1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
RadixAsteris
EINECS 253-775-4
1-(4-chlorophenoxy)-1-(1-imidazolyl)-3,3-dimethyl-2-butanone
bay-e6975
1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanone
1-(p-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanone
BAYSAN
Diadimefon
Climbazole
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Related Compounds: More...
Climbazole-d4
1185117-79-6
Chemsrc provides Climbazole(CAS#:38083-17-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Climbazole are included as well.>> amp version: Climbazole

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