(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide

Modify Date: 2025-10-09 10:05:15

(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide Structure
(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide structure
Common Name (E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide
CAS Number 3785-87-3 Molecular Weight 215.25100
Density 1.203g/cm3 Boiling Point 469.5ºC at 760 mmHg
Molecular Formula C12H13N3O Melting Point N/A
MSDS N/A Flash Point 237.8ºC

 Names

Name (Z)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.203g/cm3
Boiling Point 469.5ºC at 760 mmHg
Molecular Formula C12H13N3O
Molecular Weight 215.25100
Flash Point 237.8ºC
Exact Mass 215.10600
PSA 70.12000
LogP 1.84518
Index of Refraction 1.639
InChIKey TVPUSDGUXXMGMH-YFHOEESVSA-N
SMILES CN(C)c1ccc(C=C(C#N)C(N)=O)cc1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GD7214200
CHEMICAL NAME :
Cinnamamide, alpha-cyano-p-(dimethylamino)-
CAS REGISTRY NUMBER :
3785-87-3
LAST UPDATED :
198512
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H13-N3-O
MOLECULAR WEIGHT :
215.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,1325,1965

 Synthetic Route

~89%

(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide Structure

(E)-2-cyano-3-(...

CAS#:3785-87-3

Literature: Wang, Dong-Yue; Xi, Guo-Hong; Ma, Jing-Jun; Wang, Chun; Zhang, Xiao-Chao; Wang, Qian-Qian Synthetic Communications, 2011 , vol. 41, # 20 p. 3060 - 3065

~%

(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide Structure

(E)-2-cyano-3-(...

CAS#:3785-87-3

Literature: Mittelbach,M.; Junek,H. Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1979 , vol. 34, p. 1580 - 1586

 Synonyms

4-dimethylaminopiperidine-1-carboxylic acid tert-butyl ester
N-Boc-4-dimethylaminopiperidine
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