Abieta-8,11,13-trien-18-ol

Modify Date: 2024-01-01 23:07:15

Abieta-8,11,13-trien-18-ol structure	Common Name	Abieta-8,11,13-trien-18-ol
	CAS Number	3772-55-2	Molecular Weight	286.452
	Density	1.0±0.1 g/cm3	Boiling Point	389.4±11.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₀O	Melting Point	N/A
	MSDS	N/A	Flash Point	136.2±15.1 °C

Use of Abieta-8,11,13-trien-18-ol

Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease[1].

Name	dehydroabietadienol
Synonym	More Synonyms

Description	Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Syk Research Areas >> Inflammation/Immunology
In Vitro	Dehydroabietinol 对脾酪氨酸激酶 SYK 具有激酶抑制活性，IC50 值为 46.4 μM[1]。
References	[1]. Jun-Bo Gao, et al. Isolation, Characterization, and Structure-Activity Relationship Analysis of Abietane Diterpenoids from Callicarpa bodinieri as Spleen Tyrosine Kinase Inhibitors. J Nat Prod. 2018 Apr 27;81(4):998-1006.

Density	1.0±0.1 g/cm3
Boiling Point	389.4±11.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₀O
Molecular Weight	286.452
Flash Point	136.2±15.1 °C
Exact Mass	286.229675
PSA	20.23000
LogP	6.35
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.527