1-(4-Hydroxy-2-Methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane
Modify Date: 2024-01-20 12:23:17
1-(4-Hydroxy-2-Methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane structure
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Common Name | 1-(4-Hydroxy-2-Methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane | ||
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| CAS Number | 376362-03-7 | Molecular Weight | 326.429 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 490.3±40.0 °C at 760 mmHg | |
| Molecular Formula | C21H26O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 250.3±27.3 °C | |
Use of 1-(4-Hydroxy-2-Methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes[1]. |
| Name | 4-[3-(4-Hydroxy-2-methoxyphenyl)propyl]-2-(3-methyl-2-buten-1-yl) phenol |
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| Synonym | More Synonyms |
| Description | 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes[1]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 490.3±40.0 °C at 760 mmHg |
| Molecular Formula | C21H26O3 |
| Molecular Weight | 326.429 |
| Flash Point | 250.3±27.3 °C |
| Exact Mass | 326.188202 |
| PSA | 49.69000 |
| LogP | 5.74 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.581 |
| Hazard Codes | Xi |
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| Phenol, 4-[3-(4-hydroxy-2-methoxyphenyl)propyl]-2-(3-methyl-2-buten-1-yl)- |
| 4-[3-(4-Hydroxy-2-methoxyphenyl)propyl]-2-(3-methyl-2-buten-1-yl)phenol |