Procyanidin C1

Modify Date: 2025-08-24 16:11:20

Procyanidin C1 Structure
Procyanidin C1 structure
Common Name Procyanidin C1
CAS Number 37064-30-5 Molecular Weight 866.77200
Density 1.747g/cm3 Boiling Point N/A
Molecular Formula C45H38O18 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Procyanidin C1


Procyanidin C1 is a natural polyphenol, causes DNA damage, cell cycle arrest, and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells[1].

 Names

Name procyanidin C1
Synonym More Synonyms

 Procyanidin C1 Biological Activity

Description Procyanidin C1 is a natural polyphenol, causes DNA damage, cell cycle arrest, and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells[1].
Related Catalog
Target

Apoptosis[1]

References

[1]. Koteswari LL, et al. A comparative anticancer study on procyanidin C1 against receptor positive and receptor negative breast cancer. Nat Prod Res. 2019 Jan 8:1-8.

 Chemical & Physical Properties

Density 1.747g/cm3
Molecular Formula C45H38O18
Molecular Weight 866.77200
Exact Mass 866.20600
PSA 331.14000
LogP 4.44390
Index of Refraction 1.826
Storage condition ?20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WY9070000
CAS REGISTRY NUMBER :
37064-30-5
LAST UPDATED :
199106
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C45-H38-O18
MOLECULAR WEIGHT :
866.83

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sex chromosome loss and nondisjunction
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
200 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 246,205,1991

 Safety Information

RIDADR NONH for all modes of transport

 Synthetic Route

~98%

Procyanidin C1 Structure

Procyanidin C1

CAS#:37064-30-5

Literature: Kozikowski, Alan P.; Tuckmantel, Werner; Romanczyk JR., Leo J. Patent: US2004/116718 A1, 2004 ; Location in patent: Page 10 ;

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Procyanidin C1 Structure

Procyanidin C1

CAS#:37064-30-5

Literature: Morimoto; Nonaka; Nishioka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 633 - 642

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Detail
Literature: Morimoto; Nonaka; Nishioka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 633 - 642

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Detail
Literature: Morimoto; Nonaka; Nishioka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 633 - 642

~%

Detail
Literature: Morimoto; Nonaka; Nishioka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 633 - 642

 Articles2

More Articles
UHPLC-PDA-ESI/HRMSn profiling method to identify and quantify oligomeric proanthocyanidins in plant products.

J. Agric. Food Chem. 62(39) , 9387-400, (2014)

Oligomeric proanthocyanidins were successfully identified by UHPLC-PDA-HRMS(n) in a selection of plant-derived materials (jujube fruit, Fuji apple, fruit pericarps of litchi and mangosteen, dark choco...

A galloylated dimeric proanthocyanidin from grape seed exhibits dentin biomodification potential.

Fitoterapia 101 , 169-78, (2015)

Grape seeds are a rich source of polyphenols, especially proanthocyanidins (PACs), and are also known for the presence of galloylated oligomeric PACs (OPACs). The present study focuses on the phytoche...

 Synonyms

Procyanidol C1
(2R,3R,4S)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
Procyanidin C1
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