BigLEN(rat) TFA

Modify Date: 2024-01-10 15:25:34

BigLEN(rat) TFA Structure
BigLEN(rat) TFA structure
Common Name BigLEN(rat) TFA
CAS Number 369377-66-2 Molecular Weight 1745.98
Density N/A Boiling Point N/A
Molecular Formula C76H128N24O23 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BigLEN(rat) TFA


BigLEN(rat), one of the most abundant peptides in brain, is a potent GPR171 agonist, with an EC50 of 1.6 nM[1][2].

 Names

Name BigLEN(rat)

 BigLEN(rat) TFA Biological Activity

Description BigLEN(rat), one of the most abundant peptides in brain, is a potent GPR171 agonist, with an EC50 of 1.6 nM[1][2].
Related Catalog
In Vivo BigLEN-GPR171 system plays an important role in regulating feeding and metabolism in mice[1][2].
References

[1]. Seshat M Mack, et al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10(4):1884-1891.

[2]. Ivone Gomes, et al. GPR171 Is a Hypothalamic G Protein-Coupled Receptor for BigLEN, a Neuropeptide Involved in Feeding. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16211-6.

 Chemical & Physical Properties

Molecular Formula C76H128N24O23
Molecular Weight 1745.98
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