4-Chloro-3-fluoroaniline

Modify Date: 2025-08-25 19:20:33

4-Chloro-3-fluoroaniline Structure
4-Chloro-3-fluoroaniline structure
Common Name 4-Chloro-3-fluoroaniline
CAS Number 367-22-6 Molecular Weight 145.562
Density 1.3±0.1 g/cm3 Boiling Point 234.7±20.0 °C at 760 mmHg
Molecular Formula C6H5ClFN Melting Point 61
MSDS Chinese USA Flash Point 95.7±21.8 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name 4-Chloro-3-fluoroaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 234.7±20.0 °C at 760 mmHg
Melting Point 61
Molecular Formula C6H5ClFN
Molecular Weight 145.562
Flash Point 95.7±21.8 °C
Exact Mass 145.009460
PSA 26.02000
LogP 2.32
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.570
InChIKey ACMJJQYSPUPMPN-UHFFFAOYSA-N
SMILES Nc1ccc(Cl)c(F)c1

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H302-H311-H315-H319-H331-H335
Precautionary Statements P261-P280-P305 + P351 + P338-P311
Hazard Codes T: Toxic;Xi: Irritant;
Risk Phrases R20/21/22;R36/37/38
Safety Phrases S26-S36/37/39
RIDADR UN2811
Packaging Group III
Hazard Class 6.1
HS Code 2921420090

 Synthetic Route

~29%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Okamoto, Osamu; Kobayashi, Kensuke; Kawamoto, Hiroshi; Ito, Satoru; Yoshizumi, Takashi; Yamamoto, Izumi; Hashimoto, Masaya; Shimizu, Atsushi; Takahashi, Hiroyuki; Ishii, Yasuyuki; Ozaki, Satoshi; Ohta, Hisashi Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3282 - 3285

~98%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Ji, Pengju; Atherton, John H.; Page, Michael I. Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7471 - 7478

~98%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Silvestri, Romano; Martino, Gabriella De; Sbardella, Gianluca Organic Preparations and Procedures International, 2002 , vol. 34, # 5 p. 517 - 520

~%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Journal of the American Chemical Society, , vol. 93, # 5 p. 1190 - 1198

~%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Detail
Literature: Journal of Fluorine Chemistry, , vol. 126, # 4 p. 661 - 667

~%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Journal of the Chemical Society, , p. 423

~%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Journal of the Chemical Society, , p. 423

~%

4-Chloro-3-fluoroaniline Structure

4-Chloro-3-fluo...

CAS#:367-22-6

Literature: Organic Process Research and Development, , vol. 14, # 5 p. 1248 - 1253

 Customs

HS Code 2921420090
Summary HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

4-chloro-3-fluoro-aniline
3-Fluoro-4-Chloroaniline
MFCD01090987
4-Chloro-3-fluoro-phenylamine
3-fluoro-4-chloro-phenylamine
4-Chloro-3-fluorophenylamine
4-Chloro-3-fluoroanline
para-chloro-meta-fluoroaniline
EINECS 206-683-3
4-Chlor-3-fluor-anilin
3-F-4-Cl aniline
4-Chloro-3-fluoroaniline
Benzenamine, 4-chloro-3-fluoro-
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