oxyphyllenone a

Modify Date: 2024-01-04 11:45:58

oxyphyllenone a Structure
oxyphyllenone a structure
Common Name oxyphyllenone a
CAS Number 363610-34-8 Molecular Weight 210.27
Density 1.2±0.1 g/cm3 Boiling Point 357.8±42.0 °C at 760 mmHg
Molecular Formula C12H18O3 Melting Point N/A
MSDS N/A Flash Point 184.4±24.4 °C

 Use of oxyphyllenone a


Oxyphyllenone A is an inhibitor of NO Synthase. Oxyphyllenone A inhibits the NO production in lipopolysaccharide-activated macrophages with an IC50 of 28 μM[1].

 Names

Name (4aR,7R,8R)-7,8-dihydroxy-4a,8-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one
Synonym More Synonyms

 oxyphyllenone a Biological Activity

Description Oxyphyllenone A is an inhibitor of NO Synthase. Oxyphyllenone A inhibits the NO production in lipopolysaccharide-activated macrophages with an IC50 of 28 μM[1].
Related Catalog
References

[1]. Muraoka O, et al. Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2217-20.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 357.8±42.0 °C at 760 mmHg
Molecular Formula C12H18O3
Molecular Weight 210.27
Flash Point 184.4±24.4 °C
Exact Mass 210.125595
PSA 57.53000
LogP 0.51
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.553

 Synonyms

2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-7,8-dihydroxy-4a,8-dimethyl-, (4aR,7R,8R)-
(4aR,7R,8R)-7,8-dihydroxy-4a,8-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one
(4aR,7R,8R)-7,8-Dihydroxy-4a,8-dimethyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone