6-Bromo-2,3-difluorobenzaldehyde

Modify Date: 2024-01-06 07:46:20

6-Bromo-2,3-difluorobenzaldehyde Structure
6-Bromo-2,3-difluorobenzaldehyde structure
Common Name 6-Bromo-2,3-difluorobenzaldehyde
CAS Number 360576-04-1 Molecular Weight 220.99900
Density 1.758g/cm3 Boiling Point 225.7ºC at 760mmHg
Molecular Formula C7H3BrF2O Melting Point 39-43℃
MSDS N/A Flash Point 90.3ºC

 Names

Name 6-Bromo-2,3-difluorobenzaldehyde

 Chemical & Physical Properties

Density 1.758g/cm3
Boiling Point 225.7ºC at 760mmHg
Melting Point 39-43℃
Molecular Formula C7H3BrF2O
Molecular Weight 220.99900
Flash Point 90.3ºC
Exact Mass 219.93400
PSA 17.07000
LogP 2.53980
Index of Refraction 1.561

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
6-Bromo-2,3-difluorobenzaldehyde
Product Name:
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:6-Bromo-2,3-difluorobenzaldehyde
CAS number:360576-04-1

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
This product should be handled only by, or under the close supervision of, those properly qualified
Handling:
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C7H3BrF2O
Molecular weight: 221.0

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen fluoride, hydrogen bromide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
HS Code 2913000090

 Synthetic Route

~80%

6-Bromo-2,3-difluorobenzaldehyde Structure

6-Bromo-2,3-dif...

CAS#:360576-04-1

Literature: ELI LILLY AND COMPANY Patent: WO2004/9578 A2, 2004 ; Location in patent: Page 40 ; WO 2004/009578 A2

~83%

6-Bromo-2,3-difluorobenzaldehyde Structure

6-Bromo-2,3-dif...

CAS#:360576-04-1

Literature: MERCK PATENT GMBH Patent: WO2005/105772 A1, 2005 ; Location in patent: Page/Page column 56 ;

~57%

6-Bromo-2,3-difluorobenzaldehyde Structure

6-Bromo-2,3-dif...

CAS#:360576-04-1

Literature: Clariant GmbH Patent: US2001/50352 A1, 2001 ;

~%

6-Bromo-2,3-difluorobenzaldehyde Structure

6-Bromo-2,3-dif...

CAS#:360576-04-1

Literature: US2003/166628 A1, ;

 Customs

HS Code 2913000090
Summary HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%