8-Cyclopentyl-1,3-dimethylxanthine

Modify Date: 2024-01-06 19:11:04

8-Cyclopentyl-1,3-dimethylxanthine structure	Common Name	8-Cyclopentyl-1,3-dimethylxanthine
	CAS Number	35873-49-5	Molecular Weight	248.28100
	Density	1.332g/cm3	Boiling Point	513.1ºC at 760mmHg
	Molecular Formula	C₁₂H₁₆N₄O₂	Melting Point	250-252ºC
	MSDS	Chinese USA	Flash Point	264.1ºC

Use of 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective adenosine A1 receptor antagonist with Kis of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively[1].

Name	8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione
Synonym	More Synonyms

Description	8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective adenosine A1 receptor antagonist with Kis of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	Ki: 10.9 nM (A1 receptor), 1440 nM (A2 receptor)[1]
References	[1]. K A Jacobson, et al. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. J Med Chem. 1989 Aug;32(8):1873-9.

Density	1.332g/cm3
Boiling Point	513.1ºC at 760mmHg
Melting Point	250-252ºC
Molecular Formula	C₁₂H₁₆N₄O₂
Molecular Weight	248.28100
Flash Point	264.1ºC
Exact Mass	248.12700
PSA	72.68000
LogP	0.61790
Index of Refraction	1.607

8-Cyclopentyl-1,3-dimethylxanthine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH5093600

CHEMICAL NAME :: Theophylline, 8-cyclopentyl-

CAS REGISTRY NUMBER :: 35873-49-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H16-N4-O2

MOLECULAR WEIGHT :: 248.32

WISWESSER LINE NOTATION :: T56 BM DN FNVNVJ F1 H1 C- AL5TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 14,1202,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#06862

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XH5093600
HS Code	2933990090

Precursor 2
CAS#:5440-00-6 5,6-Diamino-1,3... CAS#:3400-45-1 Cyclopentanecar...
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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8-Cyclopentyltheophylline CPT

8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl theophylline

Theophylline,8-cyclopentyl

cyclopentyl teophylline

1,3-dimethyl-8-cyclopentylxanthine

Xanthine,8-cyclopentyl-1,3-dimethyl

8-cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione

DC Chemicals Limited
China
Product Name: CPT
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1H-Purine-2,6-dione,8-cyclopentyl-3,9-dihydro-1,3-dimethyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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