7,8,9,9-Tetradehydroisolariciresinol

Modify Date: 2024-01-04 10:26:58

7,8,9,9-Tetradehydroisolariciresinol Structure
7,8,9,9-Tetradehydroisolariciresinol structure
Common Name 7,8,9,9-Tetradehydroisolariciresinol
CAS Number 357645-16-0 Molecular Weight 356.369
Density 1.4±0.1 g/cm3 Boiling Point 587.4±50.0 °C at 760 mmHg
Molecular Formula C20H20O6 Melting Point N/A
MSDS N/A Flash Point 211.0±23.6 °C

 Use of 7,8,9,9-Tetradehydroisolariciresinol


Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively[1].

 Names

Name 7,8,9,9-Tetradehydroisolariciresinol
Synonym More Synonyms

 7,8,9,9-Tetradehydroisolariciresinol Biological Activity

Description Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively[1].
Related Catalog
References

[1]. Zhou Y, et al. Vitexins, nature-derived lignan compounds, induce apoptosis and suppress tumor growth. Clin Cancer Res. 2009 Aug 15;15(16):5161-9.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 587.4±50.0 °C at 760 mmHg
Molecular Formula C20H20O6
Molecular Weight 356.369
Flash Point 211.0±23.6 °C
Exact Mass 356.125977
PSA 96.22000
LogP 2.59
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.664

 Safety Information

Hazard Codes Xi

 Synonyms

2-Naphthalenecarboxaldehyde, 3,4-dihydro-6-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-, (3R,4S)-
(3R,4S)-6-Hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-3,4-dihydro-2-naphthalenecarbaldehyde