AG-09/1

Modify Date: 2024-01-16 13:14:48

AG-09/1 Structure
AG-09/1 structure
Common Name AG-09/1
CAS Number 356776-32-4 Molecular Weight 358.37200
Density N/A Boiling Point N/A
Molecular Formula C16H14N4O4S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

 Use of AG-09/1


AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense[1].

 Names

Name 2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(4-nitrophenyl)acetamide
Synonym More Synonyms

 AG-09/1 Biological Activity

Description AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense[1].
Related Catalog
Target

FPR1[1]

In Vitro N-formyl peptides activate phagocytes through G protein-coupled receptors known as FPR. FPR1 was the first FPR cloned and encodes a high-affinity receptor for fMLF[1].
References

[1]. Andrei I Khlebnikov, et al. Computational Structure-Activity Relationship Analysis of Small-Molecule Agonists for Human Formyl Peptide Receptors. Eur J Med Chem. 2010 Nov;45(11):5406-19.

 Chemical & Physical Properties

Molecular Formula C16H14N4O4S
Molecular Weight 358.37200
Exact Mass 358.07400
PSA 138.13000
LogP 3.80670

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synonyms

2-[(6-methoxy-1H-benzimidazol-2-yl)thio]-N-(4-nitrophenyl)-acetamide