Cyclo(L-Phe-L-Val)

Modify Date: 2024-01-08 08:56:02

Cyclo(L-Phe-L-Val) structure	Common Name	Cyclo(L-Phe-L-Val)
	CAS Number	35590-86-4	Molecular Weight	246.30
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₈N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclo(L-Phe-L-Val)

Cyclo(L-Phe-L-Val) is a potent inhibitor of enzymes isocitrate lyase (ICL) (IC50=27 μg/mL). cyclo(L-Phe-L-Val) inhibits the gene transcription of ICL in C. albicans under C2-carbon-utilizing conditions[1].

Name	cis-cyclo(Val-Phe)
Synonym	More Synonyms

Description	Cyclo(L-Phe-L-Val) is a potent inhibitor of enzymes isocitrate lyase (ICL) (IC50=27 μg/mL). cyclo(L-Phe-L-Val) inhibits the gene transcription of ICL in C. albicans under C2-carbon-utilizing conditions[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
Target	Isocitrate lyase (ICL)[1]
In Vitro	Cyclo(L-Phe-L-Val) (32 μg/mL; 2 d) 分别降低白色念珠菌 SC5314 (野生型)、MRC10 (Δicl) 和 MRC11 (Δicl + ICL) 中的 icl 产物水平[1]。
References	[1]. Kim H, et al. Inhibitory Effects of Diketopiperazines from Marine-Derived Streptomyces puniceus on the Isocitrate Lyase of Candida albicans. Molecules. 2019 Jun 4;24(11):2111.

Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.30
Exact Mass	246.13700
PSA	58.20000
LogP	1.52590

Precursor 0
DownStream 5
CAS#:72-18-4 L-Valine CAS#:63-91-2 L-Phenylalanine CAS#:4070-48-8 L-VALINE METHYL... CAS#:2577-90-4 Methyl L-phenyl...
CAS#:17585-69-2 L-Phenylalanine...

Cyclo(Val-Phe)

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