TGX-155
Modify Date: 2024-02-04 08:33:24
TGX-155 structure
|
Common Name | TGX-155 | ||
|---|---|---|---|---|
| CAS Number | 351071-90-4 | Molecular Weight | 354.37 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H19FN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TGX-155TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy[1][2][3]. |
| Name | 8-(4-fluoro-2-methylphenoxy)-2-morpholin-4-yl-1H-quinolin-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
PI3Kβ |
| In Vivo | TGX-155 (1.5 mg/kg 和 2.5 mg/kg；静脉注射；单剂量) 以时间和剂量依赖性方式显著改善了兔颈动脉损伤中的循环血流量减少 (CFRs)[3]。 |
| References |
| Molecular Formula | C20H19FN2O3 |
|---|---|
| Molecular Weight | 354.37 |
| Exact Mass | 354.13800 |
| PSA | 54.82000 |
| LogP | 4.08180 |
| tgx-155 |