3-Methoxy-5-(trifluoromethyl)aniline structure
|
Common Name | 3-Methoxy-5-(trifluoromethyl)aniline | ||
|---|---|---|---|---|
| CAS Number | 349-55-3 | Molecular Weight | 191.150 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 242.0±40.0 °C at 760 mmHg | |
| Molecular Formula | C8H8F3NO | Melting Point | 50-52 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 100.2±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 3-methoxy-5-(trifluoromethyl)aniline |
|---|---|
| Synonym | More Synonyms |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 242.0±40.0 °C at 760 mmHg |
| Melting Point | 50-52 °C(lit.) |
| Molecular Formula | C8H8F3NO |
| Molecular Weight | 191.150 |
| Flash Point | 100.2±27.3 °C |
| Exact Mass | 191.055801 |
| PSA | 35.25000 |
| LogP | 2.78 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.477 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332-H315-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | PG3 |
| WGK Germany | 3 |
| HS Code | 2922299090 |
| Precursor 3 | |
|---|---|
| DownStream 6 | |
| HS Code | 2922299090 |
|---|---|
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK).
Bioorg. Med. Chem. Lett. 18(23) , 6231-5, (2008) A series of SYK inhibitors based on the phenylamino pyrimidine thiazole lead 4 were prepared and evaluated for biological activity. Lead optimization provided compounds with nanomolar K(i)'s against S... |
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| MFCD00000393 |
| EINECS 206-487-8 |
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| 3-methoxy-5-trifluoromethylaniline |