pyroglutamyl-phenylalanyl-prolinamide
Modify Date: 2025-09-10 19:50:32
pyroglutamyl-phenylalanyl-prolinamide structure
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Common Name | pyroglutamyl-phenylalanyl-prolinamide | ||
|---|---|---|---|---|
| CAS Number | 34783-35-2 | Molecular Weight | 372.41800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H24N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of pyroglutamyl-phenylalanyl-prolinamide[Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin[1]. |
| Name | L-pyroglutamyl-L-phenylalanine-L-proline amide |
|---|---|
| Synonym | More Synonyms |
| Description | [Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin[1]. |
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| Related Catalog | |
| In Vitro | [Phe2]-TRH对 TRH 受体的亲和力低于 TRH 本身，并且在 [Phe2, azPro3]-TRH 类似物中用 azPro 替代 Pro 导致亲和力进一步损失约 200 倍[1]。 |
| References |
| Molecular Formula | C19H24N4O4 |
|---|---|
| Molecular Weight | 372.41800 |
| Exact Mass | 372.18000 |
| PSA | 121.60000 |
| LogP | 0.82670 |
| InChIKey | ZETOYWKJNIJFCR-KKUMJFAQSA-N |
| SMILES | NC(=O)C1CCCN1C(=O)C(Cc1ccccc1)NC(=O)C1CCC(=O)N1 |
| Glp-Phe-Pro-NH2 |
| pyro-L-Glu-L-Phe-L-Pro-NH2 |
| [Phe2]-TRH |
| pGlu-Phe-Pro-NH2 |