trans-Urocanic acid

Modify Date: 2025-08-27 18:12:45

trans-Urocanic acid Structure
trans-Urocanic acid structure
 Common Name trans-Urocanic acid
CAS Number 3465-72-3 Molecular Weight 138.124
Density 1.4±0.1 g/cm3 Boiling Point 456.9±20.0 °C at 760 mmHg
Molecular Formula C6H6N2O2 Melting Point N/A
MSDS N/A Flash Point 230.1±21.8 °C

 Use of trans-Urocanic acid


trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function[1].

 Names

Name (2E)-3-(1H-Imidazol-4-yl)acrylic acid
Synonym More Synonyms

 trans-Urocanic acid Biological Activity

Description trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro trans-urocanic acid (trans-UCA) partially inhibits cytotoxic function of IL-2-activated NK cells and reduces IL-2-induced activation of NK cells[1]. trans-urocanic acid (trans-UCA;100 μg/mL) slightly decreases cell proliferation and viability of primary human keratinocytes[2]. Cell Proliferation Assay[2] Cell Line: Primary human keratinocytes Concentration: 100 μg/mL Incubation Time: 24 hours Result: Decreased cell proliferation and viability.
References

[1]. J Uksila, et al. Trans-urocanic acid, a natural epidermal constituent, inhibits human natural killer cell activity in vitro. Exp Dermatol. 1994 Apr;3(2):61-5.

[2]. Kazuyo Kaneko, et al. cis-Urocanic acid enhances prostaglandin E2 release and apoptotic cell death via reactive oxygen species in human keratinocytes. J Invest Dermatol. 2011 Jun;131(6):1262-71.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 456.9±20.0 °C at 760 mmHg
Molecular Formula C6H6N2O2
Molecular Weight 138.124
Flash Point 230.1±21.8 °C
Exact Mass 138.042923
PSA 65.98000
LogP 0.01
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.674
Storage condition 2-8C

 Safety Information

HS Code 2933290090

 Synthetic Route

N/A structure

N/A

CAS#:178764-94-8

~%

trans-Urocanic acid Structure

trans-Urocanic acid

CAS#:3465-72-3

Literature: Masuda Yakugaku Zasshi, 1956 , vol. 76, p. 325,327, 328 Chem.Abstr., 1956 , p. 13880
L-Histidine structure

L-Histidine

CAS#:71-00-1

~%

trans-Urocanic acid Structure

trans-Urocanic acid

CAS#:3465-72-3

Literature: Langer, Martin; Pauling, Andrea; Retey, Janos Angewandte Chemie, 1995 , vol. 107, # 13/14 p. 1585 - 1587
1H-Imidazole-5-propanoicacid, a-chloro- structure

1H-Imidazole-5-...

CAS#:6630-42-8

~%

trans-Urocanic acid Structure

trans-Urocanic acid

CAS#:3465-72-3

Literature: Edlbacher; v.Bidder Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1942 , vol. 276, p. 126,128 Full Text Show Details Masuda Yakugaku Zasshi, 1956 , vol. 76, p. 325,327, 328 Chem.Abstr., 1956 , p. 13880
2-amino-3-(1,3,3-trimethyl-2H-imidazol-3-ium-4-yl)propanoate structure

2-amino-3-(1,3,...

CAS#:507-29-9

~%

trans-Urocanic acid Structure

trans-Urocanic acid

CAS#:3465-72-3

Literature: Valeev; Salikhov; Krasnoslobodtseva; Sharipov; Spirikhin; Tolstikov Chemistry of Natural Compounds, 2007 , vol. 43, # 2 p. 143 - 148
1H-Imidazole-4-carbaldehyde structure

1H-Imidazole-4-...

CAS#:3034-50-2

Malonic acid structure

Malonic acid

CAS#:141-82-2

~%

trans-Urocanic acid Structure

trans-Urocanic acid

CAS#:3465-72-3

Literature: Horii et al. Yakugaku Zasshi, 1954 , vol. 74, p. 408 Chem.Abstr., 1955 , p. 5451
cis-Urocanic acid structure

cis-Urocanic acid

CAS#:7699-35-6

~%

trans-Urocanic acid Structure

trans-Urocanic acid

CAS#:3465-72-3

Literature: Kpissay, Armah; Kuhl, C. Nicole; Mohammad, Taj; Haber, Ken; Morrison, Harry Tetrahedron Letters, 1997 , vol. 38, # 49 p. 8435 - 8438

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-Propenoic acid, 3-(1H-imidazol-4-yl)-, (2E)-
Trans-Urocanic acid
(E)-3-(1H-Imidazol-5-yl)-2-propenoic acid
(E)-urocanic acid
E-3-(imidazol-4-yl)propenoic acid
(2E)-3-(1H-Imidazol-4-yl)acrylic acid
(Z)-4-pyridalacetophenone
trans-4-imidazoleacrylic acid
(2E)-3-(1H-imidazol-4-yl)prop-2-enoic acid
(E)-3-(1H-imidazol-4-yl)acrylic acid
1-phenyl-3-(4-pyridinyl)-2-propen-1-one
Urocanic acid
2-propenoic acid, 3-(1H-imidazol-5-yl)-, (2E)-
3-(1H-imidazol-4-yl)prop-2-enoic acid
(E)-3-(1H-imidazol-4-yl)-2-propenoic acid
Urocanate
(E)-3-(imidazol-4-yl)acrylic acid
E-3-(4-Pyridyl)-1-phenylprop-2-en-1-on
4-Imidazoleacrylic Acid
(2E)-3-(1H-Imidazol-5-yl)acrylic acid
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

trans-Urocanic acid suppliers

Price: ￥5187/100g

Reference only. check more trans-Urocanic acid price

Related Compounds: More...
Trans-Urocanic acid
104-98-3
cis-Urocanic acid
7699-35-6
methyl urocanate
160073-02-9
ethyl 3-(1-methylimidazol-4-yl)prop-2-enoate
67879-36-1
(E)-3-(1-methyl-1H-imidazol-5-yl)-2-propenoic acid ethyl ester
67879-31-6
3-(1H-imidazol-5-yl)prop-2-enoyl chloride
91788-89-5
methyl 3-(1H-imidazol-4-yl)acrylate
52363-40-3
3-(1H-imidazol-4-yl)-2-propenoic acid methyl ester
70346-51-9
ethyl 3-(1H-imidazol-4-yl)acrylate
27538-35-8
tert-butyl 4,6-dimethyl-2,3-dihydro-1H-indole-2-carboxylate
2137458-26-3
1-[(tert-butoxy)carbonyl]-4-fluoro-5-methyl-2,3-dihydro-1H-indole-2-carboxylic acid
2137504-31-3
Methyl 3-(ethylamino)-4-oxopiperidine-1-carboxylate
2138348-88-4
3-(oxan-4-yl)-1-(piperidin-2-yl)-1H-pyrazole-4-carboxylic acid
2138348-94-2
1-{2-[Ethyl(2-methylpropyl)amino]ethyl}cyclobutane-1-carboxylic acid
2137959-60-3
tert-butyl 3-(oxan-4-yl)-1-(piperidin-3-yl)-1H-pyrazole-4-carboxylate
2137689-17-7
1-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}-3-(oxan-4-yl)-1H-pyrazole-4-carboxylic acid
2138380-01-3
tert-butyl 3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]piperidine-1-carboxylate
2138348-98-6
tert-butyl 3-(3-methyl-1H-pyrazol-1-yl)piperidine-1-carboxylate
2138342-06-8
tert-butyl 3-(3-methyl-4-nitro-1H-pyrazol-1-yl)piperidine-1-carboxylate
1823232-37-6
Chemsrc provides trans-Urocanic acid(CAS#:3465-72-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of trans-Urocanic acid are included as well.>> amp version: trans-Urocanic acid

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved