Betamipron

Modify Date: 2024-01-02 23:07:18

Betamipron structure	Common Name	Betamipron
	CAS Number	3440-28-6	Molecular Weight	193.19900
	Density	1.227 g/cm3	Boiling Point	469.2ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₁NO₃	Melting Point	132 °C
	MSDS	N/A	Flash Point	237.6ºC

Use of Betamipron

Betamipron is a chemical compound which is used together with Panipenem to inhibit Panipenem uptake into the renal tubule and prevent nephrotoxicity.

Name	3-benzamidopropanoic acid
Synonym	More Synonyms

Description	Betamipron is a chemical compound which is used together with Panipenem to inhibit Panipenem uptake into the renal tubule and prevent nephrotoxicity.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others

Density	1.227 g/cm3
Boiling Point	469.2ºC at 760 mmHg
Melting Point	132 °C
Molecular Formula	C₁₀H₁₁NO₃
Molecular Weight	193.19900
Flash Point	237.6ºC
Exact Mass	193.07400
PSA	66.40000
LogP	1.28200
Index of Refraction	1.557
Storage condition	−20°C

Betamipron MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY3272500

CHEMICAL NAME :: beta-Alanine, N-benzoyl-

CAS REGISTRY NUMBER :: 3440-28-6

BEILSTEIN REFERENCE NO. :: 2212769

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H11-N-O3

MOLECULAR WEIGHT :: 193.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3496 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 39(Suppl 3),140,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36 gm/kg/90D-C

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - changes in sodium

REFERENCE :: NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 39(Suppl 3),157,1991

WGK Germany	3
RTECS	AY3272500

Precursor 10
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DownStream 8
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Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step.

Biochemistry 43(11) , 3230-7, (2004)

Beta-benzoyl-DL-alanine was synthesized from alpha-bromoacetophenone and diethyl acetamidomalonate. The racemic amino acid was resolved by carboxypeptidase A-catalyzed hydrolysis of the N-trifluoroace...

Thermodynamic quantitative structure-activity relationship analysis for enzyme-ligand interactions in aqueous phosphate buffer and organic solvent.

Bioorg. Med. Chem. 9(8) , 1951-5, (2001)

Thermodynamic quantitative structure-activity relationships (QSAR) for chymotrypsin-ligand binding is developed, and the results are compared for the effects of organic solvent on the substrate specif...

Nephroprotective effect of betamipron on a new carbapenem, DA-1131, in rabbits.

Biopharm. Drug Dispos. 20(3) , 125-9, (1999)

The nephroprotective effect of betamipron (200 mg/kg) was evaluated after intravenous administration of a high dose of DA-1131 (200 mg/kg) to rabbits. Extensive tubular necrosis was observed without b...

3-Benzamidopropanoic acid

MFCD00037293

Benzoyl-β-alanine

3-benzamidopropionic acid

Betamipron

3-(Benzoylamino)propionic acid

Zhejiang Hangyu API Co., Ltd
China
Product Name: BENZOYL-BETA-ALANINE
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Price: ￥420/100mg

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Betamipron

Use of Betamipron

Names

Betamipron Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Synthetic Route

Precursor & DownStream

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Synonyms