N-Demethyl-α-obscurine

Modify Date: 2024-01-30 20:29:43

N-Demethyl-α-obscurine Structure
N-Demethyl-α-obscurine structure
Common Name N-Demethyl-α-obscurine
CAS Number 34399-44-5 Molecular Weight 260.375
Density 1.2±0.1 g/cm3 Boiling Point 488.2±45.0 °C at 760 mmHg
Molecular Formula C16H24N2O Melting Point N/A
MSDS N/A Flash Point 189.7±28.9 °C

 Use of N-Demethyl-α-obscurine


N-Demethyl-α-obscurine, a lycodine-type Lycopodium alkaloid, is isolated from Lycopodii Herba[1].

 Names

Name (1R,9S,10R,16R)-16-Methyl-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadec-2(7)-en-5-one
Synonym More Synonyms

 N-Demethyl-α-obscurine Biological Activity

Description N-Demethyl-α-obscurine, a lycodine-type Lycopodium alkaloid, is isolated from Lycopodii Herba[1].
Related Catalog
In Vivo N-Demethyl-α-obscurine exhibits Cmax (35.53 ng/mL), t1/2 (2.24 h), and AUC0→t (156.91 ng•h/mL) following i.g. administration (L. Herba extract; 4.8 g/kg) in rats[1].
References

[1]. Ma D, et, al. Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of Lycopodii Herba Extract by LC-MS/MS. Molecules. 2019 May 19;24(10):1930.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 488.2±45.0 °C at 760 mmHg
Molecular Formula C16H24N2O
Molecular Weight 260.375
Flash Point 189.7±28.9 °C
Exact Mass 260.188873
LogP 3.15
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.580
Storage condition 2-8℃

 Synonyms

(1R,9S,10R,16R)-16-Methyl-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadec-2(7)-en-5-one
1H-5,10b-Propano-1,7-phenanthrolin-8(7H)-one, 2,3,4,4a,5,6,9,10-octahydro-12-methyl-, (4aR,5S,10bR,12R)-