Pterosin B

Modify Date: 2025-08-23 07:49:45

Pterosin B structure	Common Name	Pterosin B
	CAS Number	34175-96-7	Molecular Weight	218.292
	Density	1.1±0.1 g/cm3	Boiling Point	396.5±41.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₈O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	169.3±20.2 °C

Use of Pterosin B

Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3[1][2].

Name	(R)-6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydro-1H-inden-1-one
Synonym	More Synonyms

Description	Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> Salt-inducible Kinase (SIK)
Target	SIK3
References	[1]. Hannah R.Dexter, et al. A concise stereoselective synthesis of pterosin B. Tetrahedron Letters, Volume 59, Issue 49, 5 December 2018, Pages 4323-4325. [2]. Yahara Y, et al. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Nat Commun. 2016 Mar 24;7:10959.

Density	1.1±0.1 g/cm3
Boiling Point	396.5±41.0 °C at 760 mmHg
Molecular Formula	C₁₄H₁₈O₂
Molecular Weight	218.292
Flash Point	169.3±20.2 °C
Exact Mass	218.130676
PSA	37.30000
LogP	2.65
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.560
InChIKey	SJNCSXMTBXDZQA-SECBINFHSA-N
SMILES	Cc1cc2c(c(C)c1CCO)C(=O)C(C)C2

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK7537730

CHEMICAL NAME :: 1-Indanone, 6-(2-hydroxyethyl)-2,5,7-trimethyl-, (-)-

CAS REGISTRY NUMBER :: 34175-96-7

LAST UPDATED :: 198703

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H18-O2

MOLECULAR WEIGHT :: 218.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human HeLa cell

DOSE/DURATION :: 100 mg/L

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 31,829,1975

Hazard Codes	Xi
HS Code	2914400090

Precursor 0
DownStream 1
CAS#:39815-60-6 2-(2,4,6-trimet...

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

1-Indanone, 6-(2-hydroxyethyl)-2,5,7-trimethyl-, (-)-

6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydro-1H-inden-1-one

1H-Inden-1-one, 2,3-dihydro-6-(2-hydroxyethyl)-2,5,7-trimethyl-

6-(2-Hydroxyethyl)-2,5,7-trimethyl-1-indanone

Pterosin B

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Pterosin B
Price: Check
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China
Product Name: Pterosin B
Price: ￥Inquiry/1g
Purity: 98.9%
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DC Chemicals Limited
China
Product Name: Pterosin B
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Pterosin B

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CHEMICAL IDENTIFICATION

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ACUTE TOXICITY DATA

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.