3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)

Modify Date: 2024-01-03 13:28:57

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) structure
Common Name 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)
CAS Number 34014-60-3 Molecular Weight 359.41600
Density 1.132g/cm3 Boiling Point 481.7ºC at 760 mmHg
Molecular Formula C20H25NO5 Melting Point N/A
MSDS N/A Flash Point 245.1ºC

 Names

Name diethyl 4-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.132g/cm3
Boiling Point 481.7ºC at 760 mmHg
Molecular Formula C20H25NO5
Molecular Weight 359.41600
Flash Point 245.1ºC
Exact Mass 359.17300
PSA 73.86000
LogP 3.38500
Index of Refraction 1.525

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7979000
CHEMICAL NAME :
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(p-methoxyphenyl)-2,6-dimethyl-, diethyl ester
CAS REGISTRY NUMBER :
34014-60-3
BEILSTEIN REFERENCE NO. :
0043785
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H25-N-O5
MOLECULAR WEIGHT :
359.46
WISWESSER LINE NOTATION :
T6M DHJ B1 CVO2 DR DO1& EVO2 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01323

 Safety Information

HS Code 2933399090

 Synthetic Route

~97%

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure

3,5-Pyridinedic...

CAS#:34014-60-3

Literature: Sivamurugan; Vinu; Palanichamy; Murugesan Heteroatom Chemistry, 2006 , vol. 17, # 4 p. 267 - 271

~80%

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure

3,5-Pyridinedic...

CAS#:34014-60-3

Literature: Murthy; Rajack, Abdul; Taraka Ramji; Jeson Babu; Praveen, Ch.; Aruna Lakshmi Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 18 p. 6016 - 6023

~36%

Detail
Literature: Angeles-Beltran, Deyanira; Lomas-Romero, Leticia; Lara-Corona, Victor H.; Gonzalez-Zamora, Eduardo; Negron-Silva, Guillermo Molecules, 2006 , vol. 11, # 10 p. 731 - 738

~%

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure

3,5-Pyridinedic...

CAS#:34014-60-3

Literature: Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268

~%

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure

3,5-Pyridinedic...

CAS#:34014-60-3

Literature: Borsche; Hahn Justus Liebigs Annalen der Chemie, 1939 , vol. 537, p. 219,242 Full Text Show Details Berson; Brown Journal of the American Chemical Society, 1955 , vol. 77, p. 444,446

~%

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure

3,5-Pyridinedic...

CAS#:34014-60-3

Literature: Da Silva; Goncalves; Ferre; Sena; Coelho; Junior, J. Jones Heterocyclic Communications, 2009 , vol. 15, # 1 p. 57 - 59

~%

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) Structure

3,5-Pyridinedic...

CAS#:34014-60-3

Literature: Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

diethyl 2,6-dimethyl-4-p-methoxyphenyl-1,4-dihydropyridine-3,5-dicarboxylate
Ftorin
diethyl 1,4-dihydro-2,6-dimethyl-4-(4-methoxyphenyl)pyridine-3,5-dicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylic acid diethyl ester
diethyl 2,6-dimethyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SK&Ftorin (pharmaceutical)
4-(2-Trifluoromethylphenyl)-3,5-dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine
4-<2-(trifluoromethyl)phenyl>-3,5-dicarboethoxy-1,4-dihydrolutidine
diethyl 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]3,5-pyridinedicarboxylate
3,5-dicarbethoxy-1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)pyridine
2,6-Dimethyl-3,5-dicarbomethoxy-4-(o-trifluoromethylphenyl)-1,4-dihydropyridine [French]
diethyl 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
diethyl 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-pyridine-3,5-dicarboxylate
4-(4-methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
3,5-diethoxycarbonyl-4-(4-methoxy)phenyl-2,6-dimethyl-1,4-dihydropyridine