Rapid and cleaner synthesis of 1, 4??dihydropyridines in aqueous medium

V Sivamurugan, A Vinu, M Palanichamy…

Index: Sivamurugan; Vinu; Palanichamy; Murugesan Heteroatom Chemistry, 2006 , vol. 17, # 4 p. 267 - 271

Full Text: HTML

Citation Number: 31

Abstract

Abstract The present investigation deals with a novel water soluble Lewis acid complex, Zn [(L) proline] 2 catalyzed Hantzsch 1, 4-dihydropyridine derivatives syntheses in aqueous medium assisted by microwave irradiation. The microwave promoted syntheses in aqueous medium afforded moderate to excellent yield (up to 98%) within short reaction time and allowed the reaction to take place with low microwave power (200 W). This synthetic ...