5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine
Modify Date: 2025-12-01 02:35:49
5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine structure
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Common Name | 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine | ||
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| CAS Number | 338965-09-6 | Molecular Weight | 346.214 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 476.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C16H13Cl2N5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 241.8±28.7 °C | |
Use of 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamineHepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC50<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias[1]. |
| Name | 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine |
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| Synonym | More Synonyms |
| Description | Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC50<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias[1]. |
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| Related Catalog | |
| Target |
IC50: <50 μM (hepcidin)[1] |
| References |
[1]. Franz DÜRRENBERGER, et al. Novel pyrimidine and triazine hepcidine antagonists. WO2011026835 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 476.1±45.0 °C at 760 mmHg |
| Molecular Formula | C16H13Cl2N5 |
| Molecular Weight | 346.214 |
| Flash Point | 241.8±28.7 °C |
| Exact Mass | 345.054810 |
| LogP | 1.90 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.691 |
| 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine |
| 4,6-Pyrimidinediamine, 5-[(2,4-dichlorophenyl)methyl]-2-(2-pyridinyl)- |
| 5-[(2,4-Dichlorophenyl)methyl]-2-(2-pyridinyl)-4,6-pyrimidinediamine |
| MFCD00231629 |