Notum-IN-1

Modify Date: 2025-08-27 11:06:05

Notum-IN-1 structure	Common Name	Notum-IN-1
	CAS Number	338419-11-7	Molecular Weight	244.08
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₇Cl₂N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Notum-IN-1

Notum-IN-1 (compound 6b) is an orally active, selective and brain penetrant inhibitor of Notum. Notum-IN-1 blocks the Wnt signaling in vivo in mouse[1].

Name	Notum-IN-1

Description	Notum-IN-1 (compound 6b) is an orally active, selective and brain penetrant inhibitor of Notum. Notum-IN-1 blocks the Wnt signaling in vivo in mouse[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	Notum[1]
References	[1]. Willis NJ, et al. Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J Med Chem. 2022 May 26;65(10):7212-7230.

Molecular Formula	C₉H₇Cl₂N₃O
Molecular Weight	244.08
InChIKey	DMIRTDWEKUNBDX-UHFFFAOYSA-N
SMILES	OCc1cn(-c2ccc(Cl)c(Cl)c2)nn1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methanol
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