8-Deoxygartanin

Modify Date: 2025-08-21 09:50:58

8-Deoxygartanin Structure
8-Deoxygartanin structure
 Common Name 8-Deoxygartanin
CAS Number 33390-41-9 Molecular Weight 380.434
Density 1.3±0.1 g/cm3 Boiling Point 595.7±50.0 °C at 760 mmHg
Molecular Formula C23H24O5 Melting Point N/A
MSDS N/A Flash Point 207.2±23.6 °C

 Use of 8-Deoxygartanin


8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3].

 Names

Name 8-desoxygartanin
Synonym More Synonyms

 8-Deoxygartanin Biological Activity

Description 8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3].
Related Catalog
Target

p65:11.3 μM (IC50)

References

[1]. Khaw KY, et al. Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies. Phytomedicine. 2014 Sep 25;21(11):1303-9.

[2]. Ngouamegne ET, et al. Endodesmiadiol, a friedelane triterpenoid, and other antiplasmodial compounds from Endodesmia calophylloides. Chem Pharm Bull (Tokyo). 2008 Mar;56(3):374-7.

[3]. Han AR, et al. Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). J Nat Prod. 2009 Nov;72(11):2028-31.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 595.7±50.0 °C at 760 mmHg
Molecular Formula C23H24O5
Molecular Weight 380.434
Flash Point 207.2±23.6 °C
Exact Mass 380.162384
PSA 90.90000
LogP 5.35
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.637

 Safety Information

Hazard Codes Xi
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

9H-Xanthen-9-one, 1,3,5-trihydroxy-2,4-bis(3-methyl-2-buten-1-yl)-
8-Deoxygartanin
1,3,5-Trihydroxy-2,4-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
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