Tesetaxel

Modify Date: 2025-09-18 12:45:21

Tesetaxel structure	Common Name	Tesetaxel
	CAS Number	333754-36-2	Molecular Weight	881.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₆₀FN₃O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tesetaxel

Tesetaxel is a orally active, semisynthetic microtubule inhibitor of the taxane class for the treatment of cancer, including colorectal and gastric cancer.

Name	Tesetaxel
Synonym	More Synonyms

Description	Tesetaxel is a orally active, semisynthetic microtubule inhibitor of the taxane class for the treatment of cancer, including colorectal and gastric cancer.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Shionoya M, Jimbo T, Kitagawa M, Soga T, Tohgo A. DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Cancer Sci. 2003;94(5):459-466. [2]. Saif MW, Sarantopoulos J, Patnaik A, Tolcher AW, Takimoto C, Beeram M. Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011;68(6):1565-1573.

Description

Tesetaxel is a orally active, semisynthetic microtubule inhibitor of the taxane class for the treatment of cancer, including colorectal and gastric cancer.

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

References

[1]. Shionoya M, Jimbo T, Kitagawa M, Soga T, Tohgo A. DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Cancer Sci. 2003;94(5):459-466.

[2]. Saif MW, Sarantopoulos J, Patnaik A, Tolcher AW, Takimoto C, Beeram M. Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011;68(6):1565-1573.

Molecular Formula	C₄₆H₆₀FN₃O₁₃
Molecular Weight	881.99
InChIKey	MODVSQKJJIBWPZ-VLLPJHQWSA-N
SMILES	CC(=O)OC12COC1CCC1(C)C3OC(CN(C)C)OC3C3=C(C)C(OC(=O)C(O)C(NC(=O)OC(C)(C)C)c4ncccc4F)CC(O)(C(OC(=O)c4ccccc4)C12)C3(C)C

(2R,4S,6S,7R,10R,13S,14R,15S,16S,18S)-13-Acetoxy-4-[(dimethylamino)methyl]-18-{[(2R,3S)-3-(3-fluoro-2-pyridinyl)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoyl]oxy}-16-hydroxy-7,19,2 ;0,20-tetramethyl-3,5,11-trioxapentacyclo[14.3.1.0.0.0]icos-1(19)-en-15-yl benzoate

2-Pyridinepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-3-fluoro-α-hydroxy-, (2aS,2bR,3S,4S,6S,8aR,10S,11aS,11bR,13aR)-2a-(acetyloxy)-3-(benzoyloxy)-10-[(dimethylamino)methyl]-2a,2b,3 ,4,5,6,8a,11a,11b,12,13,13a-dodecahydro-4-hydroxy-7,11b,14,14-tetramethyl-4,8-methano-2H-[1,3]dioxolo[3,4]cyclodeca[1,2-d]-1-benzoxet-6-yl ester, (αR,βS)-

Tesetaxel

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: tesetaxel
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Tesetaxel
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tesetaxel
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Tesetaxel

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.