VU0029251

Modify Date: 2025-08-23 21:58:29

VU0029251 structure	Common Name	VU0029251
	CAS Number	330819-85-7	Molecular Weight	237.344
	Density	1.5±0.1 g/cm3	Boiling Point	501.7±60.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₁N₃S₂	Melting Point	N/A
	MSDS	USA	Flash Point	257.2±32.9 °C

Use of VU0029251

VU0029251 is a mGluR5 partial antagonist (Ki: 1.07 μM). VU0029251 inhibits glutamate induced calcium mobilization in HEK293 cell membranes expressing rat mGluR5 (IC50: 1.7 μM)[1].

Name	VU0029251
Synonym	More Synonyms

Description	VU0029251 is a mGluR5 partial antagonist (Ki: 1.07 μM). VU0029251 inhibits glutamate induced calcium mobilization in HEK293 cell membranes expressing rat mGluR5 (IC50: 1.7 μM)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR5[1].
References	[1]. Rodriguez, A.L., et al. Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity. Mol. Pharmacol. 78(6), 1105-1123 (2010).

Density	1.5±0.1 g/cm3
Boiling Point	501.7±60.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₁N₃S₂
Molecular Weight	237.344
Flash Point	257.2±32.9 °C
Exact Mass	237.039444
LogP	4.31
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.745

MFCD00698485

5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine, 6,7-dihydro-2-(methylthio)-

VU0029251

2-(Methylsulfanyl)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine

6,7-dihydro-2-(methylthio)-5h-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine

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DC Chemicals Limited
China
Product Name: VU0029251
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Purity: 98.0%
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VU0029251

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.