JR-AB2-011

Modify Date: 2024-02-27 19:27:49

JR-AB2-011 Structure
JR-AB2-011 structure
Common Name JR-AB2-011
CAS Number 329182-61-8 Molecular Weight 398.282
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H14Cl2FN3OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JR-AB2-011


JR-AB2-011 is a potent and selective inhibitor of mTORC2 kinase activity. It markedly reduces mTORC2 signaling and IC50 while enhancing apoptotic levels in GBM cells.

 Names

Name 3-(3,4-Dichlorophenyl)-1-(4-fluorophenyl)-1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)urea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C17H14Cl2FN3OS
Molecular Weight 398.282
Exact Mass 397.021881
LogP 4.89
Index of Refraction 1.660

 Synonyms

Urea, N'-(3,4-dichlorophenyl)-N-(4,5-dihydro-5-methyl-2-thiazolyl)-N-(4-fluorophenyl)-
3-(3,4-Dichlorophenyl)-1-(4-fluorophenyl)-1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)urea
N'-(3,4-dichlorophenyl)-N-(4-fluorophenyl)-N-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)urea