Sabiporide hydrochloride

Modify Date: 2025-08-27 18:49:55

Sabiporide hydrochloride structure	Common Name	Sabiporide hydrochloride
	CAS Number	324758-66-9	Molecular Weight	408.37800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₉F₃N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sabiporide hydrochloride

Sabiporide hydrochloride is a NHE-1 inhibitor (Ki: 50 nM). Sabiporide hydrochloride has cardioprotective and neuroprotective effects. Sabiporide hydrochloride inhibits glutamate- or NMDA-induced neuronal cell death[1][2].

Name	N-(diaminomethylidene)-4-[4-(1H-pyrrole-2-carbonyl)piperazin-1-yl]-3-(trifluoromethyl)benzamide
Synonym	More Synonyms

Description	Sabiporide hydrochloride is a NHE-1 inhibitor (Ki: 50 nM). Sabiporide hydrochloride has cardioprotective and neuroprotective effects. Sabiporide hydrochloride inhibits glutamate- or NMDA-induced neuronal cell death[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
References	[1]. Touret N, et al. Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects. Eur J Pharmacol. 2003 Jan 17;459(2-3):151-8. [2]. Park HS, et al. Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia. Brain Res. 2005 Nov 2;1061(1):67-71.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Research Areas >> Neurological Disease

References

[1]. Touret N, et al. Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects. Eur J Pharmacol. 2003 Jan 17;459(2-3):151-8.

[2]. Park HS, et al. Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia. Brain Res. 2005 Nov 2;1061(1):67-71.

Molecular Formula	C₁₈H₁₉F₃N₆O₂
Molecular Weight	408.37800
Exact Mass	408.15200
PSA	121.80000
LogP	2.99690
InChIKey	SRRHGTUDJFMQIV-UHFFFAOYSA-N
SMILES	NC(N)=NC(=O)c1ccc(N2CCN(C(=O)c3ccc[nH]3)CC2)c(C(F)(F)F)c1

Sabiporide

UNII-U52APA00X7

Sabiporide HCl

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Sabiporide hydrochloride

Use of Sabiporide hydrochloride

Names

Sabiporide hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.